지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제17권 제5호
- 발행연도
- 1994.1
- 수록면
- 343 - 347 (5page)
이용수
초록· 키워드
오류제보하기
Effects of betaine on glutamate-induced neurotoxicity were examined on primary culturs of chicken embryonic brain cells and on rat cortical cultures. Betaine was found to attenuate glutamate-induced neurotoxicity both morphologically and biochemically. A 30 min exposure of chicken embryonic brain cells cultured for 12 days to 500 .mu.M glutamate produced wide-spread acute neuronal swelling and neurtic fragmentation. A 2-h pretreatment of cultured chicken embryonic brain cells with i mM betaine prior to a 30 min exposure to 500 , mu, M glutamate significantly raised the survival rate of neurons in the culture. When chicken embryonic brain cells were pretreated for 2 h with i mM betaine followed by exposure to 100 .mu.M glutamate for 42 h, lactate dehydrogenase levels within the cells remained at 62% of .mu.M untreated control values while glutamate-treated control fell to 0% lactate dehydrogenase. Betaine also exerted attenuating effects on N-methyl-D-asparte-, kainate-and quisqualate-induced neurotoxicity in a similar manner to that observed with glutamate. Similar neuroprotective effects of betaine with rat cortical cultures.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effects of betaine on the glutamate-induced neurotoxicity in primary cultured chicken brain cells
한국응용약물학회 신약개발 연구발표회
1993 .01
-
일차배양 뇌세포를 이용한 글루타메이트성 신경에 작용하는 천연물의 검색방법
약학회지
1995 .01
-
Ginsenosides Rb_1_ and Rg_3_ Attenuate Glutamate-induced Neurotoxicity in Primary Cultures of Rat Cortical Cells
International Symposium on Ginseng
1998 .09
-
Constituents from Hedyotis diffusa protect against glutamate-induced neurotoxicity in primary cultures of rat cortical cells
대한약학회 학술대회
2000 .01
-
Effects of Lycii Fructus on Primary Cultured Chicken Brain Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1991 .01
-
일차배양한 계배 뇌세포 내의 콜린성 신경에 대한 인삼 Dammarane계 Glycosides의 작용
약학회지
1994 .01
-
Neuroprotective effects of hexane extract from Uncaria sinensis against glutamate-induced neurotoxicity in primary cultured cortical neurons
대한체질인류학회 학술대회 연제 초록
2012 .05
-
Phenylpropanoids from Scrophularia buergeriana Protect Cultured Rat Cortical Neurons from Glutamate-Induced Neurotoxicity
대한약학회 학술대회
2000 .01
-
A Pharmaco-toxicological Study of Vitamin E on Amyloid β Protein-induced Neurotoxicity in Embryonic Chick Cortex Cell Culture
한국실험동물학회 학술발표대회 논문집
1998 .04
-
빌로바라이드가 글루타메이트에 의한 신경독성에 미치는 영향
약학회지
1997 .01
-
Flavonoids of Inula britannica attenuate the glutamate-induced toxicity in primary cultures of rat cortical cells
대한약학회 학술대회
2001 .01
-
Protective Effects of Ginsenosides on Cyanide-induced Neurotoxicity in Cultured Rat Cerebellar Granule Cells
Journal of Ginseng Research
2000 .12
-
Ginsenoside Rg₃ Attenuate Neurotoxicity Induced by Cholesterol Oxide
고려인삼학회 학술대회
2010 .12
-
대뇌피질 신경세포에 미치는 glutamate 독성에 대한 한약재 효능연구
한국한의학연구원 논문집
1998 .12
-
ETHANOL-EXTRACTED PROPOLIS ATTENUATES KAINATE-INDUCED NEUROTOXICITY VIA ADENOSINE A1 RECEPTOR IN THE RAT
한국실험동물학회 학술발표대회 논문집
2001 .06
-
Ginseng extracts attenuates neurotoxicity and ameliorates cognitive impairment induced by D-galactose in rats
고려인삼학회 학술대회
2009 .05
-
Ceramide is Linked to Glutamate-induced Cell Death in Cultured Cortical Neurons
대한약학회 학술대회
2001 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0