지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제17권 제3호
- 발행연도
- 1994.1
- 수록면
- 204 - 206 (3page)
이용수
초록· 키워드
오류제보하기
A regioselective perparation of 10-methoxy-11-hydroxyaporphine ("Apocodeine, 1b") form (R, S)-10, 11-dihydroxyaporphine(apomorphine, 1a) is described. The isopropylidene ketal ring of 10, 11-(isopropylidenyldioxy) aporphine (2) obtained by the isopropylidenation of apomorphine, was regioselectively opened by the ten equivalent of timethylaluminum to give 100-hydroxy-11-t-butyloxyaporphine (3). The free 10-hydroxyl position of 3 was methylated with methyl p-toluenesulfonate/NaH, and afforded 10-methoxy-11-t-butyloxyaporphine (4) in high yield. Selective debutylation gave the desired 10-methoxy-11-hydroxyaporphine("apocodeine", 1b) in good yield.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Synthesis of Substituted Pyridine-2, 4-dione Nucleosides
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1992 .01
-
Inhibitory Effects of Aporphine Alkaloids on Dopamine Biosynthesis in PC12 cells
대한약학회 학술대회
2002 .01
-
Di-acetyl-nor-aporphines: Novel molecules and a novel mechanism to inhibit melanogenesis
대한화장품학회 학술대회
2003 .01
-
항염작용이 기대되는 새로운 피롤리딘닐 1,2-벤조티아진 유도체의 합성
약학회지
1997 .01
-
Synthesis of 6-Hydroxy-7-methoxy-4-oxo-4H-chromene-2-carboxylic acid N-Alkyl Amides and their Antioxidant Activity
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
-
3-메톡시-6-알릴치오피리다진의 사람 췌장암 세포 사멸작용
약학회지
2005 .01
-
Single Oral Toxicity Study of 3-Methoxy-6-Allylthiopyridazine in Rats
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2005 .01
-
정신분열병환자의 발병연령과 항정신병약물 투여전후의 혈장 Homovanillic acid, 3-methoxy-4-hydroxyphenylglycol농도의 연관성
신경정신의학
2003 .01
-
Total Synthesis of a Norneolignan from Ratanhia Radix
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2002 .01
-
The suppressive effect of (2S)-2'-methoxy kurarinoneon RANKL-induced osteoclastogenesis
대한체질인류학회 학술대회 연제 초록
2013 .05
-
Proteomic Analysis and the Antimetastatic Effect of N-(4methyl)phenyl-O-(4-methoxy) phenyl-thionocarbamate-Induced Apoptosis in Human Melanoma SK-MEL-28 cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
-
Synthesis and Antitubercular Activity of 6-Chloro (Unsubstituted)- 2-Methoxy-9-Substituted Acridine Derivatives
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Refinement of the structure of naproxen, (+)-6- methoxy-$\alpha$-methyl-2-naphthaleneacetic acid
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1987 .01
-
Chemical Constituents from the Stems of Morinda citrifolia Linn
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Improved One-pot Regioselective Synthesis of 3,7-Diarylpyrazolo[1,5-α]pyrimidines and Their CB1R Activity
대한화장품학회지
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0