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자료유형
학술저널
저자정보
Jeong, Hyun-Ja (College of Pharmacy, VCRC of Wonkwang University,College of Oriental Medicine, Kyung Hee University) Hwang, Gab-Soo (School of Civil and Environmental Engineering, Kunsan National University) Myung, No-Il (College of Pharmacy, VCRC of Wonkwang University) Lee, Joon-Ho (College of Pharmacy, VCRC of Wonkwang University) Lee, Ju-Young (College of Pharmacy, VCRC of Wonkwang University) Um, Jae-Young (College of Oriental Medicine, Kyung Hee University) Kim, Hyung-Min (College of Oriental Medicine, Kyung Hee University) Hong, Seung-Heon (College of Pharmacy, VCRC of Wonkwang University)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제6권 제1호
발행연도
2006.1
수록면
39 - 44 (6page)

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Ji-Jang-Soo (JJS) is known to have a detoxification effect. However, it is still unclear how JJS has these effects in experimental models. In this study, we investigated the effect of JJS on the viability of cells and production of cytokines in human T-cell line, MOLT-4 cells, and human mast cell line, HMC-1 cells. The MOLT-4 cells were cultured for 24 h in the presence or absence of JJS. As the result, JJS (1/100 dilution) significantly increased the cell viability about 78% (P < 0.05) and also increased the interleukin (IL)-2, and interferon $(IFN)-{\gamma}$ production compared with media control at 24 h. But had no effect on IL-4 production. Hypoxia mimic compound, desferroxamine (DFX) decreased the immune cell viability. Cell viability decreased by DFX was increased by JJS. In conclusion, these data indicate that JJS may have an immune-enhancing effect.

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