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논문 기본 정보

자료유형
학술저널
저자정보
Lim, Jung-Sun (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Jeong, Sung-Young (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Hwang, Ji-Yoon (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Cho, Kyu-Hyuk (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Cho, Jae-Woo (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Han, Sang-Seop (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Song, Chang-Woo (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Yoon, Seok-Joo (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology)
저널정보
대한독성유전단백체학회 Molecular & cellular toxicology Molecular & cellular toxicology 제1권 제2호
발행연도
2005.1
수록면
106 - 110 (5page)

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N-ethyl-N-nitrosourea (ENU), which is a toxin and a carcinogen, as well as a mutagen, has a variety of effects on mice. ENU induces point mutation in male germ cell. Number of mutant animals are developed with ENU treatment. However, potentiality ot ENU as a carcinogen is not fully understood, even though, mutagenicity of ENU is broadly studied, In the present study, the gene expression profiling and histopathological investigation of ENU treated mouse's liver and brain were investigated. Also, the expression patterns of cancer related genes in ENU-treated mouse were analyzed.

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