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자료유형
학술저널
저자정보
Vasu, Vihas T. (Department of Biochemistry, Faculty of Science, M.S. University) Ashwinikumar, C. (Department of Biochemistry, Faculty of Science, M.S. University) Maroo, Jyoti (Department of Biochemistry, Faculty of Science, M.S. University) Gupta, Sharad (Consulting Pathologist, Guptas laboratory, Sumangal Chambers) Gupta, Sarita (Department of Biochemistry, Faculty of Science, M.S. University)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제3권 제2호
발행연도
2003.1
수록면
84 - 89 (6page)

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The antidiabetic efficacy of Enicostemma littorale Blume (chhota chirayata) aqueous extract was examined in newly diagnosed non-insulin-dependent diabetes mellitus (NIDDM) patients taking only the extract and was administered as two divided doses, half an hour before meal as 5g of aqueous extract per single dose. Out of the 20 patients volunteered, 11 successfully completed the 2 month trial and a significant decrease in fasting & postprandial blood glucose and glycosylated haemoglobin levels were observed along with a significant improvement in the antioxidant parameters of the patients. There was also a significant increase in serum insulin levels in 7 patients after extract treatment as compared to levels before treatment. Serum total cholesterol and serum triglyceride levels were decreased significantly with a significant increase in serum HDLCholesterol levels. Other vital parameters remained stable and no side effects were observed. This is the first report showing the hypoglycemic, antioxidant and hypolipidemic properties of the aqueous extract of E. littorale Blume in non-insulin dependent diabetes mellitus patients.

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