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논문 기본 정보

자료유형
학술저널
저자정보
Chung, Hwan-Suck (College of Pharmacy, Wonkwang University, and KI Co., Ltd.) Koo, Hyun-Na (College of Pharmacy, Wonkwang University, and KI Co., Ltd.) Moon, Young-Hoe (Department of Clinical Pathology, Wonkwang University School of Medicine) Kim, Hyung-Min (College of Pharmacy, Wonkwang University, and KI Co., Ltd.)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제3권 제1호
발행연도
2003.1
수록면
18 - 20 (3page)

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초록· 키워드

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The purpose of this study was to examine the effect of supplementary highly purified chitosan (HPC) on blood alcohol concentration in healthy human. The human study was performed with two sections. Each section of the study was conducted by two-phase cross-over design with a week wash-out period. All volunteers took HPC in one phase, and took a placebo in the next phase. Blood alcohol concentrations were different between in those taking HPC and in those taking the placebo in the human. And the concentration of serum aspartate aminotransferase (AST, GOT) and alanine aminotransferase (ALT, GPT), the indicator of liver cell damage, was lowered in those taking HPC, compared to those taking the placebo. In conclusion, taking HPC prior to drinking alcohol can somewhat reduce alcohol concentration in human blood and liver cell damage.

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