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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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Th study the influence of transcatheter hepatic embolization on glucose metabolism, glucose tolerance tests were performed in hepatoma. Ten patients had hepatoma without chronic liver disease(control group), twelve patients had hepatoma with chronic liver disease(CLD group), adn twenty-eight patients had diabetes mellitus with hepatoma(diabetic group). Glucose tolerance tests were done before and after embolization therapy using Lipiodol and/or Gelfoam. The author evaluated changes of glucose tolerance after oral glucose loading, and the relationship between fasting blood glucose(FBG) and the liver function(SGPT value) in three groups, before and after embolotherapy. In the control group, the glucose tolerance was not altered significanly. However, the glucose tolerance after embolotherapy was significantly impaired at 60,90, and 120 minutes after glucose loading(p<0.05) in the CLD group. In the diabetic group, there were impairment of glucose tolerance at 30,60,90,120 and 180 minutes after glucose loading(p<0.01). There was no significant relationship between the liver function(SGPT value) and FBG. From the results, the author concluded that embolotherapy for hepatoma sometimes can cause significant impairment of glucose tolerance, especially in the patients with chronic liver disease and advanced diabetes mellitus. Therefore, careful management of diabetes before and after embolotherapy should be carried out for improvement of the patient's grognosis.
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