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논문 기본 정보

자료유형
학술저널
저자정보
임낙철 (대전대학교 부속한방병원)
저널정보
대전대학교 한의학연구소 논문집 : 대전대학교 한의학연구소. 한의학편 논문집 : 대전대학교 한의학연구소. 한의학편 제8권 제2호
발행연도
2000.1
수록면
361 - 374 (14page)

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초록· 키워드

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This study was done to elucidate the antioxidant activities of Polygoni Radix rubra(赤何首烏) by way of aqua-acupuncture methods. After 10% & 20% concentrations of liquid extract of Polygoni Radix rubra(PRR) were acupunctured on Joksamri(足三里) of rats with acute and chronic experimental oxidation by AAPH(2, 2' -azobis (aminoidinopropane), hydrochloride), various kinds of experiments were performed. The results were obtained as follows: 1. In acute oxidant experiment, the amount of TBARS was significantly increased from 0.5 hr to 1.5 hr after AAPH treatment 2. In acute oxidant experiment by AAPH, uric acid as significantly increased while the others didn't show any difference such as total protein, albumin, bilirubin. 3. In chronic oxidant experiment by AAPH, PRR significantly increased the body weight in comparison with control group, whereas liver and spleen tended to increase, lung and kidneys tended to decrease. 4. In chronic oxidant experiment by AAPH, PRR significantly decreased the GPT, hemolysis of erythrocytes, TBA and BUN, where GOT was significantly reduced in 20% PRR treated group, and TG was significantly in 10% PRR treated group. These results suggest that PRR has potent antioxidant activity and needs more studies on microsomal fraction of liver and kidney.

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