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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 1999.1
- 수록면
- 1 - 7 (7page)
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Gonadotropin-releasing hormone (GnRH) was originally isolated as a hypothalamic peptide that regulates reproduction by stimulating the release of gonadotropins. Using comparative animal models has led to the discovery that GnRH has a more ancient evolutionary origin. Durinq evolution GnRH peptide underwent gene duplication and structural changes to give rise to multiple molecular forms of GnRHs. Mammalian GnRH initially considered to be the sole molecular form, is now grouped as a family of peptides along with GnRH variants determined from representatives in all classes of vertebrates. Vertebrate species including primates and humanshave more than one GnRH variant in individual brains; a unique GnRH form in the forebrain and chicken IIGnRH in the midbrain. Furthermore, several species of bony fish have three molecular variants of GnRH: salmon GnRH sea-bream GnRH and chicken II GnRH. Also, it has been shown that in addition to the olfactory placodes and the midbrain, there is a third embryonic source of GnRH neurons from the basal diencephalon in birds and fish, which might be true for other vertebrates. Therefore, comparative animal models like fish with discrete sites of expression of three molecular variants of GnRH in individual brains, could provide insight into novel functions of GnRH variants, conservation of gene regulation, and mechanisms governing reproduction in vertebrates.
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Gonadotropin-Releasing Hormone (GnRH) Neuron-Specific Splicing of GnRH Transcript
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Expression and Regulation of Gonadotropin-Releasing Hormone(GnRH) and Its Receptor mRNA Transcripts During the Mouse Ovarian Development
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In vivo regulation of gonadotropin-releasing hormone (GnRH) gene expression by GnRH analogs in ovariectomized, estradiol-primed rats
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시상하부 GnRH 뉴런의 신경내분비학적 연구
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Molecular Co-evolution of Gonadotropin-releasing Hormones and Their Receptors
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Immunocontraceptive Effects in Male Rats Vaccinated with Gonadotropin-Releasing Hormone-I and -II Protein Complex
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Changes of Gonadotrophin Releasing Hormone(GnRH) and GnRH-receptor mRNA Expression in Hypothalamus and Testis of Puberty and Mature Rat by Chronic Alcohol Exposure
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Alteraation of Gonadotropin-releasing Hormone and Luteinizing Hormone ${\beta}$-Subunit mRNA Levels in Neonatally Estrogenized Female Rats
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Mechanism of GnRH pre-m RNA Splicing
한국동물학회 뉴스레터
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GnRH Expressions during Fetal Ovarian Development in Mouse
한국동물학회 학술대회
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Seasonal Changes in Gonadotropin Releasing Hormone(GnRH) levels in bullfrog brain
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Neuroendocrine Integration of Hypothalamic GnRH Neurons
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양서류의 GnRH 와 그 수용체에 대한 분자생물학적 연구
한국동물학회 학술대회
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참개구리, 북방산개구리, 옴개구리 뇌에서 3가지 생식소 자극 호르몬 분비 호르몬(mGnRH, sGnRH, cGnRH II )의 분포
동물학회지
1994 .01
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Cloning and sequencing of cDNA encoding GnRH in Rana dybowskii
한국동물학회 학술대회
1996 .01
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Cloning andi sequencing of cDNA encoding a novel form of gonadotropin releasing hormone (amphibian GnRH) in the frog (Rana dybowskii)
한국동물학회 학술대회
1997 .01
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Regulation of GnRH gene expression by MNDA and Nitric oxide in immortalized GTI-1 neuronal cells
한국동물학회 학술대회
1995 .01
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Deep Brain Photoreceptors and Photoperiodism in Vertebrates
Journal of photoscience : an international journal officail organ of the korean society of photoscience
2002 .01
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