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안성복; 최원; 김철준; 최성준; 이강희; 하경수; 김현창

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자료유형: 학술저널

저자정보: 안성복 (연세대학교 의과대학 예방의학교실) 최원 (한국 엠에스디 의학부) 김철준 (한국 엠에스디 의학부) 최성준 (사노피 신데라보 코리아 의학부) 이강희 (보건복지부 국제협력팀) 하경수 (연세대학교 의과대학 예방의학교실) 김현창 (연세대학교 의과대학 예방의학교실)

저널정보: 한국의료질향상학회 한국의료질향상학회지 한국의료질향상학회지 제12권 제1호

발행연도: 2006.1

수록면: 52 - 61 (10page)

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Background : The promotion and advertisement of pharmaceuticals should be based on evidence from clinical trials. We conducted this study to assess whether the pharmaceutical advertisement claims in Korean medical journals had relevant references, and whether the claims were supported by the references. Methods : We reviewed pharmaceutical advertisements in five Korean medical journals issued during the first half of 1999 and during the first half of 2004. Three investigators independently reviewed the advertisements to see whether the studies quoted to endorse the advertising messages supported the corresponding claims. Using multiple logistic regression analyses, we investigated which factors were associated with the quality of the advertisement claims. Results : From the 550 advertisements in the five journals, we identified 157 different advertisements and 475 different promotional claims. Only 149 claims had at least one reference, and 105 claims had references of published article. We could find supporting evidences in the 90 claims. The factors which were associated with the quality of advertisement claims were category of drugs, category of claims, and the manufacturer characteristics. Claims for cardiovascular and endocrine drugs, and claims on efficacy, and claims of multinational company were more evidence-based. Conclusion : Majority of the pharmaceutical advertisement claims in Korea did not have appropriate references. Drug category, claim category, and the manufacturer characteristics were associated with the quality of advertisement claims, and the manufacturer characteristics was the most important determinants.

#Quality #Evidence #Pharmaceutical

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소속기관 연세대학교 의과대학 예방의학교실

주요연구분야 의약학 > 기초의학 > 예방의학·직업환경의학 의약학 > 임상의학 > 방사선과학

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소속기관 한국 엠에스디 의학부