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논문 기본 정보

자료유형
학술저널
저자정보
양익 (한림대학교 의과대학 방사선과학교실) 정수영 (한림대학교 의과대학 방사선과학교실) 박해정 (한림대학교 의과대학 방사선과학교실) 이열 (한림대학교 의과대학 방사선과학교실) 정봉화 (한림대학교 의과대학 외과학교실) 심정원 (한림대학교 의과대학 병리학교실)
저널정보
대한영상의학회 대한방사선의학회지 대한방사선의학회지 제37권 제4호
발행연도
1997.1
수록면
757 - 762 (6page)

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Purpose : To assess the usefulness of 3D-gradient echo dynamic contrast enhanced MRI (3D-DMRI) in the diagnosis of breast cancer and to determine the most useful parameter for this diagnosisMaterials and Methods : Using a 1.0T MR unit, (Magnetom, Sienens, Erlaugen, Germany), 3D-DMRI (TR/TE=30/12) with Gd-DTPA was performed in 38 cases of breast cancer, 22 of fibroadenoma, and in three normal volunteers. We retrospectively evaluated the findings according to the speed on dynamic study and maximal amount of contrast enhancement during the delayed phase;we calculated the three diagnostic parameters.Results : On conventional spin-echo T1- and T2-weighted imaes, there was no significant difference of signal intensity brtween benign fibroadenoma and breast carcinoma. Rapid contrast enhancement (within one minute) was benign in 35 breast cancer lesions (92.1%), but relatively low and slow contrast enhancement (after five minutes) was noted in three such lesions (7.9%). Gradual contrast enhancement was noted in 21 lesions of fibroadenoma (95.5%), but a moderate degree of rapid contrast enhancement (from three to five minutes) was noted in the other case (7.9%). of On the delayed enhanced phase of 3D-DMRI, the maximal amount of contrast enhancement showed no significant difference between fibroadenoma and cancer. On 3D-DMRI, an irregular, spiculated border, with high contrast enhancement was noted in all cases of breast cancer, in particular, irregular thick peripheral contrast enhancement with central necrosis was noted 11 cases (28.9%).Conclusion : For the diagnosis of breast cancer, 3D-DMRI is a useful technique. Among the diagnostic criteria of speed, maximal amount of contrast enhancement and morphology, morphologic change after contrast enhancement study was the most useful diagnostic parameter.

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