지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 저널정보
- 대한약학회 대한약학회 학술대회 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
- 발행연도
- 2003.1
- 수록면
- 1,103 - 1,103 (1page)
이용수
초록· 키워드
오류제보하기
In the previous studies, we have reported that NQ30l, a synthetic l,4-naphthoquinone derivative, displayed a potent antithrombotic activity, and that this might be due to antiplatelet effect, which was mediated by inhibition of cytosolic $Ca^{2+}$ mobilization in activated platelets. In the present study, the effect of NQ301 on arachidonic acid cascade in activated platlets was examined. NQ301 concentration-dependently inhibited washed rabbit platelet aggregation induced by collagen (10 $\mu$g/ml), arachidonic acid (100 $\mu$M) and U46619 (1 $\mu$M), a thromboxane $A_2$receptor agonist, with $IC_50$ values of 0.60$\pm$0.02, 0.79$\pm$0.04 and 0.58$\pm$0.04 $\mu$M, respectively. (omitted)
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effect of NQ304, an Antithrombotic Agent, on the Arachidonic Acid Metabolism in Rabbit Platelet Aggregation
대한약학회 학술대회
2002 .01
-
Antiplatelet Activity of NQ12 May Be Mediated by Inhibition of Cyclooxygenase and Generation of 12-HETE
대한약학회 학술대회
2002 .01
-
Inhibition of rabbit platelet aggregation by CMR 32
한국실험동물학회 학술발표대회 논문집
2017 .02
-
A Novel Antithrombotic Agent, NQ304 Inhibits the Proliferation of Vascular Smooth Muscle Cells
대한약학회 학술대회
2002 .01
-
Vitamin K Antagonist, NQ12 Inhibits PDGF-BB-Induced MAP Kinases Activation in Rat Aortic Vascular Smooth Muscle Cells
대한약학회 학술대회
2002 .01
-
Anti-platelet Effect of Black Tea Extract via Inhibition of TXA2 in Rat
대한의생명과학회지
2019 .12
-
Antiplatelet and Antithrombotic Activities of Korean Red Ginseng
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
-
Effects of Tetrandrine and Fangchinoline on Human Platelet Aggregation, Thromboxane B$_2$ Formation and Blood coagulation.
한국응용약물학회 추계학술발표논문집
1998 .01
-
Further Investigation of the Action Mechanism of GS 389: a Thromboxane $A_2$ Antagonistic Action
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1995 .01
-
정상 및 허혈/재관류 흰쥐 심장에 대한 2-클로로-3-(4-시아노페닐아미노 )-1,4-나프토퀴논 ( NQ-Y15 )의 작용
약학회지
1997 .01
-
Gallocatechin Gallate Inhibits Platelet Aggregation by Arachidonic Acid Liberation and $TxA_2$ Synthase Activity
대한약학회 학술대회
2003 .01
-
Effects of Green Tea Catehins and (-)-Epigallocatechin Gallate on Rabbit Platelet Aggregation and Thromboxane B2 Formation
대한약학회 학술대회
2002 .01
-
Inhibition of Growth Factor-induced MAP kinase and Akt Activation in Rat Aortic Vascular Smooth Muscle Cells by NQ304, a 1,4-Naphthoquinone Derivative
대한약학회 학술대회
2001 .01
-
Antiplatelet and Antithrombotic Effects of the Extract of Lindera obtusiloba Leaves
Biomolecules & Therapeutics(구 응용약물학회지)
2016 .01
-
한국의 소아 아토피 천식에서 Thromboxane A2 수용체(T924C) 유전자다형과 폐기능과의 관련성
천식 및 알레르기
2005 .01
-
Platelet Anti-aggregating Triterpene and Sterol Constituents from the Leaves of Acanthopanax senticosus
대한약학회 학술대회
2003 .01
-
Carrier-Mediated Tissue Distribution and Blood-Brain Barrier Transport of New Quinolones
한국응용약물학회 춘계학술발표논문집
1997 .01
-
Perilla oil improves blood flow through inhibition of platelet aggregation and thrombus formation
Laboratory Animal Research
2014 .03
-
양파와 알로에 복합물이 혈소판 응집에 미치는 영향
약학회지
2014 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0