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논문 기본 정보

자료유형
학술대회자료
저자정보
Hahn, Byung-Dong (Functional Ceramics Research Group, Korea Institute of Materials Science) Park, Dong-Soo (Functional Ceramics Research Group, Korea Institute of Materials Science) Lee, Jeong-Min (Functional Ceramics Research Group, Korea Institute of Materials Science) Choi, Jong-Jin (Functional Ceramics Research Group, Korea Institute of Materials Science) Ryu, Jung-Ho (Functional Ceramics Research Group, Korea Institute of Materials Science) Yoon, Woon-Ha (Functional Ceramics Research Group, Korea Institute of Materials Science) Lee, Byoung-Kuk (Functional Ceramics Research Group, Korea Institute of Materials Science) Choi, Joon-Hwan (School of Materials Science and Engineering, Seoul National University) Kim, Hyoun-Ee (School of Materials Science and Engineering, Seoul National University)
저널정보
한국재료학회 한국재료학회 학술발표대회 한국재료학회 2009년도 추계학술발표대회
발행연도
2009.1
수록면
411 - 411 (1page)

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Aerosol Deposition (AD) is anovel way to fabricate bioactive ceramic coatings in biomedical implants and prostheses applications. In the present work, silicon-substituted hydroxyapatite (HA) coatings on commercially pure titanium were prepared by aerosol deposition using Si-HA powders. The incorporation of silicon in the HA lattice is known to improve the bioactivity of the HA, makingsilicon-substitute HA an attractive alternative to pure HA in biomedical applications. Si-HA powders with the chemical formula $Ca_{10}(PO_4)_6-x(SiO_4)x(OH)_2-x$, having silicon contents up to x=0.5 (1.4 wt%), were synthesized by solid-state reaction of $Ca_2P_2O_7$, $CaCO_3$, and $SiO_2$. The Si-HA powders were characterized by X-ray diffraction (XRD), X-ray fluorescence spectrometry (XRF), and Fourier transform infrared spectroscopy(FT-IR). The corresponding coatings were also analyzed by XRD, scanning electron microscopy (SEM), and electron probe microanalyzer (EPMA). The results revealed that a single-phase Si-HA was obtained without any secondary phases such as $\alpha$- or $\beta$-tricalcium phosphate (TCP) for both the powders and the coatings.The Si-HA coating was about $5\;{\mu}m$ thick, had a densemicrostructure with no cracks or pores. In addition, the proliferation and alkaline phosphatase (ALP) activity of MC3T3-E1 preosteoblast cells grown on the Si-HA coatings were significantly higher than those on the bare Ti and pure HA coating. These results revealed the stimulatory effects induced by siliconsubstitution on the cellular response to the HA coating.

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