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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 20 - 29 (10page)
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Cell death is now reclassified into several types based on the mechanisms and morphologic phenotype. Understanding of such classifications offers insights into the pathogenesis of liver disease, as well as diagnostic or therapeutic implications. Apoptosis is recognized relatively easily due to its unique morphology, but lytic cell death may occur in the form of accidental necrosis, mitochondria permeability transition-driven necrosis, necroptosis, pyroptosis, ferroptosis, and parthanatos. The cell may be engulfed by neighboring cells due to a loss of integrin signaling or cancer cell competition by entosis, a type of cell death. The classification also includes mechanistically termed cell death such as autophagy-dependent cell death and lysosome-dependent cell death. These different types of cell death may occur uniquely in certain liver diseases but may coexist in the evolution of the disease. They occur in parenchymal and non-parenchymal liver cells, as well as inflammatory cells, causing distinct pathologic consequences. This review briefly covers the recently revised classifications of cell death and discusses their relevance to liver diseases of different etiologies.
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참고문헌 (78)
참고문헌 신청
Galluzzi L / 2018 / Molecular mechanisms of cell death : recommendations of the Nomenclature Committee on Cell Death 2018 / Cell Death Differ 25:486~541
Wang S / 2016 / A mechanistic review of cell death in alcohol-induced liver injury / Alcohol Clin Exp Res 40:1215~1223
Luedde T / 2014 / Cell death and cell death responses in liver disease : mechanisms and clinical relevance / Gastroenterology 147:765~783
Canbay A / 2003 / Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression / Hepatology 38:1188~1198
Canbay A / 2002 / Fas enhances fibrogenesis in the bile duct ligated mouse : a link between apoptosis and fibrosis / Gastroenterology 123:1323~1330
Wang S / 2016 / A mechanistic review of cell death in alcohol-induced liver injury / Alcohol Clin Exp Res 40:1215~1223
Luedde T / 2014 / Cell death and cell death responses in liver disease : mechanisms and clinical relevance / Gastroenterology 147:765~783
Canbay A / 2003 / Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression / Hepatology 38:1188~1198
Canbay A / 2002 / Fas enhances fibrogenesis in the bile duct ligated mouse : a link between apoptosis and fibrosis / Gastroenterology 123:1323~1330
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