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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 542 - 546 (5page)
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Purpose: The prevalence and clinical outcomes of asymptomatic carotid artery stenosis (CAS) in patients with coronary arterydisease (CAD) have not been thoroughly studied. We examined the prevalence and predictors of asymptomatic CAS detected bycarotid angiography and determined the impact of concomitant CAS on prognosis in patients undergoing coronary angiography(CAG) due to CAD. Materials and Methods: Between January 2013 and July 2015, 395 patients who underwent carotid digital subtraction angiographyto screen for CAS during CAG were analyzed. The presence of CAS was defined as angiographically significant stenosis(≥50%). Major adverse cardiac and cerebrovascular event (MACCE) rates were compared between patients with and withoutCAS. MACCEs included a composite of cardiac death, cerebrovascular death, acute myocardial infarction, and stroke. Results: Of the 395 patients, 101 (25.5%) patients had significant CAS. The independent predictors of CAS were age, male sex, hypertension,diabetes, and multi-vessel disease. In patients with CAD, the presence of CAS was as an independent predictor forMACCEs after adjusting for confounding factors (hazard ratio 2.47, 95% confidence interval 1.16–5.24, p=0.018). Conclusion: Asymptomatic CAS was documented in up to 25% of patients with CAD. The presence of CAS in patients with CADwas associated with a higher rate of MACCEs. Therefore, detection of CAS by carotid angiography during CAG may be importantfor risk stratification for CAD patients, particularly those with multi-vessel disease.
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참고문헌 (10)
참고문헌 신청
Yamagishi M / 2000 / Morphology of vulnerable coronary plaque : insights from follow-up of patients examined by intravascular ultrasound before an acute coronary syndrome / J Am Coll Cardiol 35:106~111
Cohen GI / 2013 / Relationship between carotid disease on ultrasound and coronary disease on CT angiography / JACC Cardiovasc Imaging 6:1160~1167
Akosah KO / 2006 / Carotid ultrasound for risk clarification in young to middle-aged adults undergoing elective coronary angiography / Am J Hypertens 19:1256~1261
Grotta JC / 2013 / Clinical practice. Carotid stenosis / N Engl J Med 369:1143~1150
North American Symptomatic Carotid Endarterectomy Trial Collaborators / 1991 / Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis / N Engl J Med 325:445~453
Cohen GI / 2013 / Relationship between carotid disease on ultrasound and coronary disease on CT angiography / JACC Cardiovasc Imaging 6:1160~1167
Akosah KO / 2006 / Carotid ultrasound for risk clarification in young to middle-aged adults undergoing elective coronary angiography / Am J Hypertens 19:1256~1261
Grotta JC / 2013 / Clinical practice. Carotid stenosis / N Engl J Med 369:1143~1150
North American Symptomatic Carotid Endarterectomy Trial Collaborators / 1991 / Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis / N Engl J Med 325:445~453
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