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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 31 - 37 (7page)
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Clostridial bacteria are zoonotic agents, which cause severe necrotizing enteritis, pseudo-membrane col-itis, enterotoxemia to both humans and animals. The objective of this study was to monitor the antibiotic resistance of Clostridium isolates on clinical specimens from wild animals in Seoul zoo for 5 years. Clostridium isolates were verified by using Vitek2 compact machine. Antibiotic susceptibility was as-sessed by antibiotic disc diffusion test, which was followed by Kirby-Bauer disc diffusion test method. The frequency of Antimicrobial resistance of Clostridium isolate was the greatest in gentamicin (87%), then in order of amikacin (80%). There were 55.6% of Clostridium isolates showed multiple drug resist-ance (MDR). These results showed that a lot of Clostridial bacteria from wild animals in Seoul zoo were acquired antibiotic resistance. Because of the wild animal’s aggressive manner, it has been hard to collect clinical samples from wild animals in a zoo to exam antibiotic susceptibility. For these reasons, empirical use of antibiotics has been performed in frequently. It may cause to increase the emergence of antibiotic resistance bacteria. In addition, the antibiotic resistance bacteria from zoo animals can be spread to other wild animals which inhabit around the zoo. Therefore, regular monitoring of antibiotic resistance Clostridial bacteria is important to protect animals and humans from Clostridial diseases.
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참고문헌 (21)
참고문헌 신청
Albertini MT / 2002 / Surveillance of methicillin-resistant Staphylococcus aureus(MRSA)and Enterobacteriaceae producing extended-spectrum beta-lactamase(ESBLE)in Northern France : a five-year multicentre incidence study / J Hosp Infect 52(2):107~113
Alekshun MN / 2004 / Targeting virulence to prevent infection : to kill or not to kill? Drug Discov / Today Ther Strateg 1:483~489
Alexander CJ / 1995 / Identification and antimicrobial resistance patterns of clinical isolates of Clostridium clostridioforme, Clostridium innocuum and Clostridium ramosen compared with these of clinical isolates of Clostridium perfringens / J Clin Microbiol 33(12):3209~3215
British Society for Antimicrobial Chemotherapy(BSAC) / 2011 / Methods for antimicrobial susceptibility testing, Version 10.2 / BSAC
Bulger RJ / 1968 / Decreased incidence of antibiotic resistance among Staphylococcus aureus : a study in a university hospital over a 9-year period / Annals of internal medicine 69(6):1099~1108
Alekshun MN / 2004 / Targeting virulence to prevent infection : to kill or not to kill? Drug Discov / Today Ther Strateg 1:483~489
Alexander CJ / 1995 / Identification and antimicrobial resistance patterns of clinical isolates of Clostridium clostridioforme, Clostridium innocuum and Clostridium ramosen compared with these of clinical isolates of Clostridium perfringens / J Clin Microbiol 33(12):3209~3215
British Society for Antimicrobial Chemotherapy(BSAC) / 2011 / Methods for antimicrobial susceptibility testing, Version 10.2 / BSAC
Bulger RJ / 1968 / Decreased incidence of antibiotic resistance among Staphylococcus aureus : a study in a university hospital over a 9-year period / Annals of internal medicine 69(6):1099~1108
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