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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 51 - 58 (8page)
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Osteoradionecrosis of the skull base (SB-ORN) is a serious potentially lethal complication after radiotherapy in the head and neck region and is therefore considered one of the most challenging clinical entities among skull base lesions. Management options includes nasal irrigation, medications such as systemic antibiotics and anti-inflammatory drugs, hyperbaric oxygen therapy, and surgical debridement. Despite these efforts treatment outcomes are associated with a poor prognosis. Recent studies have shown an increased disease control rate with a more aggressive surgical approach including sequestrectomy. One of the main factors associated with poor prognosis is involvement of the internal carotid artery near the skull base. Spontaneous carotid rupture is frequently associated with death and/or severe morbidity and also poses risk of profuse bleeding during surgery. In this article we will deliver a comprehensive review of SB-ORN, including pathophysiology, clinical features, and an update in treatment strategy.
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참고문헌 (38)
참고문헌 신청
Chang KP / 2000 / Endoscopic management of skull base osteoradionecrosis / Laryngoscope 110(7):1162~1165
Liu J / 2019 / Endoscopic sequestrectomy for skull base osteoradionecrosis in nasopharyngeal carcinoma patients : A 10-year experience / Int J Clin Oncol 24(3):248~255
Gossman W / Osteoradionecrosis / StatPearls Publishing
Raggio BS / 2018 / Modern management of osteoradionecrosis / Curr Opin Otolaryngol Head Neck Surg 26(4):254~259
Rivero JA / 2017 / Osteoradionecrosis: A review of pathophysiology, prevention and pharmacologic management using pentoxifylline, α-tocopherol, and clodronate / Oral Surg Oral Med Oral Pathol Oral Radiol 124(5):464~471
Liu J / 2019 / Endoscopic sequestrectomy for skull base osteoradionecrosis in nasopharyngeal carcinoma patients : A 10-year experience / Int J Clin Oncol 24(3):248~255
Gossman W / Osteoradionecrosis / StatPearls Publishing
Raggio BS / 2018 / Modern management of osteoradionecrosis / Curr Opin Otolaryngol Head Neck Surg 26(4):254~259
Rivero JA / 2017 / Osteoradionecrosis: A review of pathophysiology, prevention and pharmacologic management using pentoxifylline, α-tocopherol, and clodronate / Oral Surg Oral Med Oral Pathol Oral Radiol 124(5):464~471
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