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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 1 - 7 (7page)
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Pruritus is a common symptom in psoriasis. However, few studies have assessed the characteristics of pruritus according to morphological phenotypes of psoriasis. Objective: To investigate the characteristics of pruritus according to morphological phenotypes of psoriasis and to assess the association with inflammatory mediators related to pruritus. Methods: Psoriasis patients were divided into 2 groups according to clinical phenotype: eruptive inflammatory (EI) and chronic stable (CS). Clinical data of pruritus were assessed by an itch questionnaire. Serum neuropeptides and cytokines including substance P, histamine, vasoactive intestinal peptide, neuropeptide Y, calcitonin gene-related peptide and interleukin-31 (IL-31) were quantitatively measured. Results: In total, 50 patients with psoriasis (30 male, 20 female; mean age, 45.7 years) were studied (EI, n=15 and CS, n=35). Pruritus was reported by 80% of EI and CS patients. There were no significant differences in prevalence of pruritus, pruritus intensity, severity of psoriasis, serum neuropeptides, or IL-31 between the 2 groups. Conclusion: The morphological phenotype does not seem to be an important factor affecting the prevalence and characteristics of pruritus in psoriasis.
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참고문헌 (30)
참고문헌 신청
Amatya B / 2008 / Patients' perspective of pruritus in chronic plaque psoriasis : a questionnaire-based study / J Eur Acad Dermatol Venereol 22:822~826
Yosipovitch G / 2000 / The prevalence and clinical characteristics of pruritus among patients with extensive psoriasis / Br J Dermatol 143:969~973
Krueger G / 2001 / The impact of psoriasis on quality of life : results of a 1998National Psoriasis Foundation patient-membership survey / Arch Dermatol 137:280~284
Reich A / 2007 / Mediators of pruritus in psoriasis / Mediators Inflamm 2007:64727
Potenzieri C / 2012 / Basic mechanisms of itch / Clin Exp Allergy 42:8~19
Yosipovitch G / 2000 / The prevalence and clinical characteristics of pruritus among patients with extensive psoriasis / Br J Dermatol 143:969~973
Krueger G / 2001 / The impact of psoriasis on quality of life : results of a 1998National Psoriasis Foundation patient-membership survey / Arch Dermatol 137:280~284
Reich A / 2007 / Mediators of pruritus in psoriasis / Mediators Inflamm 2007:64727
Potenzieri C / 2012 / Basic mechanisms of itch / Clin Exp Allergy 42:8~19
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