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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives: The outbreak of coronavirus disease 2019 (COVID-19) is one of the main public health challenges currently facing the world. Because of its high transmissibility, COVID-19 has already caused extensive morbidity and mortality in many countries throughout the world. An accurate estimation of the basic reproduction number (R0) of COVID-19 would be beneficial for prevention programs. In light of discrepancies in original research on this issue, this systematic review and meta-analysis aimed to estimate the pooled R0 for COVID-19 in the current outbreak. Methods: International databases (including Google Scholar, Science Direct, PubMed, and Scopus) were searched to identify studies conducted regarding the R0 of COVID-19. Articles were searched using the following keywords: “COVID-19” and “basic reproduction number” or “R0.” The heterogeneity among studies was assessed using the I2 index, the Cochran Q test, and T2. A random-effects model was used to estimate R0 in this study. Results: The mean reported R0 in the identified articles was 3.38±1.40, with a range of 1.90 to 6.49. According to the results of the random-effects model, the pooled R0 for COVID-19 was estimated as 3.32 (95% confidence interval, 2.81 to 3.82). According to the results of the meta-regression analysis, the type of model used to estimate R0 did not have a significant effect on heterogeneity among studies (p=0.81). Conclusions: Considering the estimated R0 for COVID-19, reducing the number of contacts within the population is a necessary step to control the epidemic. The estimated overall R0 was higher than the World Health Organization estimate.
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참고문헌 (42)
참고문헌 신청
Huang C / 2020 / Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China / Lancet 395(10223):497~506
Pan F / 2020 / Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia / Radiology 295(3):715~721
Boldog P / 2020 / Risk assessment of novel coronavirus COVID-19 outbreaks outside China / J Clin Med 9(2):571
Chen N / 2020 / Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study / Lancet 395(10223):507~513
Chan JF / 2020 / A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission : a study of a family cluster / Lancet 395(10223):514~523
Pan F / 2020 / Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia / Radiology 295(3):715~721
Boldog P / 2020 / Risk assessment of novel coronavirus COVID-19 outbreaks outside China / J Clin Med 9(2):571
Chen N / 2020 / Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study / Lancet 395(10223):507~513
Chan JF / 2020 / A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission : a study of a family cluster / Lancet 395(10223):514~523
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