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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제30권 제6호
- 발행연도
- 2020.1
- 수록면
- 912 - 919 (8page)
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초록· 키워드
오류제보하기
Hardy kiwifruits (Actinidia arguta Planch.) have high amounts of antioxidants, including ascorbic acid (vitamin C) and phenolics. The anti-cholinesterase activity and neuroprotective effects of three different cultivars of hardy kiwifruits, cv. Mansu (A. arguta × A. deliciosa), cv. Haeyeon (A. arguta), and cv. Chiak (A. arguta), on PC-12 and SH-SY5Y cells were evaluated. Extraction of phenolics and vitamin C was carried out using 80% (v/v) aqueous ethanol and metaphosphoric acid assisted with homogenization, respectively. Hardy kiwifruit of cv. Mansu showed higher total phenolic, total flavonoid, and vitamin C contents and antioxidant capacity compared to the other two cultivars of hardy kiwifruits, cv. Haeyeon and cv. Chiak. Analysis of high-performance liquid chromatography results revealed the presence of procyanidin B2, (−)-epicatechin, neochlorogenic acid, cryptochlorogenic acid, rutin, hyperoside, isoquercitrin, and astragalin in hardy kiwifruits. The three cultivars of hardy kiwifruits had a wide range of vitamin C content of 55.2−130.0 mg/100 g fresh weight. All three cultivars of hardy kiwifruits had protective effects on neuronal PC-12 and SHSY5Y cells exposed to hydrogen peroxide by increasing cell viability and reducing intracellular oxidative stress. Furthermore, the hardy kiwifruits inhibited acetylcholinesterase and butyrylcholinesterase. Collectively, these results suggest that hardy kiwifruits rich in antioxidants like phenolics and vitamin C have good potential as functional materials in neuroprotective applications.
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참고문헌 (33)
참고문헌 신청
Li H-Y / 2018 / Phenolic profiles, antioxidant capacities, and inhibitory effects on digestive enzymes of different kiwifruits / Molecules 23:2957
Nishiyama I / 2004 / Varietal difference in vitamin C content in the fruit of kiwifruit and other Actinidia species / J. Agric. Food Chem 52:5472~5475
Latocha P / 2011 / Genotypic difference in postharvest characteristics of hardy kiwifruit (Actinidia arguta and its hybrids), as a new commercial crop Part I. Sensory profiling and physicochemical differences / Food Res. Int. 44:1936~1945
Wojdyło A / 2017 / Phytochemical compounds and biological effects of Actinidia fruits / J. Funct. Foods 30:194~202
이인일 / 2015 / 국내 육성 참다래의 항산화능 및 PC-12 신경세포 보호 효과 / 원예과학기술지 33(2):259~267
Nishiyama I / 2004 / Varietal difference in vitamin C content in the fruit of kiwifruit and other Actinidia species / J. Agric. Food Chem 52:5472~5475
Latocha P / 2011 / Genotypic difference in postharvest characteristics of hardy kiwifruit (Actinidia arguta and its hybrids), as a new commercial crop Part I. Sensory profiling and physicochemical differences / Food Res. Int. 44:1936~1945
Wojdyło A / 2017 / Phytochemical compounds and biological effects of Actinidia fruits / J. Funct. Foods 30:194~202
이인일 / 2015 / 국내 육성 참다래의 항산화능 및 PC-12 신경세포 보호 효과 / 원예과학기술지 33(2):259~267
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