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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제29권 제11호
- 발행연도
- 2019.1
- 수록면
- 1,841 - 1,851 (11page)
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초록· 키워드
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Garcinol, a well-known medicinal phytochemical, was extracted and isolated from the dried fruit rinds of Garcinia quaesita Pierre. In this study, garcinol has successfully used to reduce silver ions to silver in order to synthesize garcinol-capped silver nanoparticles (G-AgNPs). The formation and the structure of G-AgNPs were confirmed by UV-visible spectroscopy, transmission electron microscopy and Fourier transform infrared spectroscopy. The antimicrobial activity of garcinol and G-AgNPs were investigated by well diffusion assays, broth micro-dilution assays and time-kill kinetics studies against five microbial species, including Staphylococcus aureus (ATCC 25923), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922), Candida albicans (ATCC 10231) and clinically isolated methicillin-resistant Staphylococcus aureus (MRSA). The formation of G-AgNPs is a promising novel approach to enhancing the biological activeness of silver nanoparticles, and to increase the water solubility of garcinol which creates a broad range of therapeutic applications.
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참고문헌 (67)
참고문헌 신청
Kim JS / 2007 / Antimicrobial effects of silver nanoparticles / Nanomedicine 3:95~101
Ruparelia JP / 2008 / Strain specificity in antimicrobial activity of silver and copper nanoparticles / Acta Biomater 4:707~716
Sharma VK / 2009 / Silver nanoparticles : green synthesis and their antimicrobial activities / Adv. Colloid Interface Sci 145:83~96
El Nour KMA / 2010 / Synthesis and applications of silver nanoparticles / Arabian J. Chem 3:135~140
Dos Santos CA / 2014 / Silver nanoparticles : therapeutical uses, toxicity, and safety issues / J. Pharm. Sci 103:1931~1944
Ruparelia JP / 2008 / Strain specificity in antimicrobial activity of silver and copper nanoparticles / Acta Biomater 4:707~716
Sharma VK / 2009 / Silver nanoparticles : green synthesis and their antimicrobial activities / Adv. Colloid Interface Sci 145:83~96
El Nour KMA / 2010 / Synthesis and applications of silver nanoparticles / Arabian J. Chem 3:135~140
Dos Santos CA / 2014 / Silver nanoparticles : therapeutical uses, toxicity, and safety issues / J. Pharm. Sci 103:1931~1944
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