지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 729 - 738 (10page)
이용수
초록· 키워드
오류제보하기
Autophagy is an important process for protein recycling. Oligomerization of p62/SQSTM1 is an essential step in this process and is achieved in two steps. Phox and Bem1p (PB1) domains can oligomerize through both basic and acidic surfaces in each molecule. The ZZ-type zinc finger (ZZ) domain binds to target proteins and promotes higheroligomerization of p62. This mechanism is an important step in routing target proteins to the autophagosome. Here, we determined the crystal structure of the PB1 homo-dimer and modeled the p62 PB1 oligomers. These oligomer models were represented by a cylindrical helix and were compared with the previously determined electron microscopic map of a PB1 oligomer. To accurately compare, we mathematically calculated the lead length and radius of the helical oligomers. Our PB1 oligomer model fits the electron microscopy map and is both bendable and stretchable as a flexible helical filament.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Adams, P. D. / 2010 / PHENIX : a comprehensive Python-based system for macromolecular structure solution / Acta Crystallogr. D Biol. Crystallogr 66:213~221
Bitto, A. / 2014 / P62/SQSTM1 at the interface of aging, autophagy, and disease / Age (Dordr) 36:9626
Cha-Molstad, H. / 2015 / Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding / Nat. Cell Biol 17:917~929
Ciuffa, R. / 2015 / The selective autophagy receptor p62forms a flexible filamentous helical scaffold / Cell Rep 11:748~758
Emsley, P. / 2010 / Features and development of Coot / Acta Crystallogr. D Biol. Crystallogr 66:486~501
Bitto, A. / 2014 / P62/SQSTM1 at the interface of aging, autophagy, and disease / Age (Dordr) 36:9626
Cha-Molstad, H. / 2015 / Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding / Nat. Cell Biol 17:917~929
Ciuffa, R. / 2015 / The selective autophagy receptor p62forms a flexible filamentous helical scaffold / Cell Rep 11:748~758
Emsley, P. / 2010 / Features and development of Coot / Acta Crystallogr. D Biol. Crystallogr 66:486~501
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Purification, crystallization, and preliminary X-ray diffraction data analysis for PB1 dimer of P62/SQSTM1
Biodesign
2018 .01
-
Separation, analysis and applied research of oligomers contained in nylon 6, 66
한국분석과학회 학술대회
2022 .11
-
Characterization of amyloid beta oligomers using atomic force microscopy
한국진공학회 학술발표회초록집
2016 .08
-
원화추출물(PB-81)의 소 로타바이러스 설사병에 대한 항바이러스 및 치료효과
생명과학회지
2024 .06
-
A highly self-healable polyurethane synthesized by urea oligomer with excellent long-term storage stability
한국진공학회 학술발표회초록집
2020 .08
-
Lead isotope measurement using a multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS)
지질학회지
2018 .06
-
Residue Y70 of the Nitrilase Cyanide Dihydratase from Bacillus pumilus Is Critical for Formation and Activity of the Spiral Oligomer
Journal of Microbiology and Biotechnology
2016 .12
-
α-Synuclein Disrupts Vesicle Fusion by Two Mutant-Specific Mechanisms
Molecules and Cells
2022 .11
-
Isolation and Characterization of Pb-Solubilizing Bacteria and Their Effects on Pb Uptake by Brassica juncea: Implications for Microbe- Assisted Phytoremediation
Journal of Microbiology and Biotechnology
2018 .01
-
Monitoring of styrene oligomers as indicators of polystyrene plastics pollution in the North-West Pacific Ocean
한국분석과학회 학술대회
2020 .06
-
다양한 입자크기의 PVC 미세플라스틱에서 Cr과 Pb의 흡착특성 비교
대한지질학회 학술대회
2021 .10
-
Petrogenesis of lavas from Mokolo-Kosséhone region, northernmost segment of the Cameroon Volcanic Line: constraints from major/trace elements and Sr-Nd-Pb isotopic data
Geosciences Journal
2023 .04
-
저어콘 U-Pb 연대측정을 활용한 양산단층의 운동시기 제한
대한지질학회 학술대회
2022 .10
-
SHRIMP U-Pb 저어콘 연대측정 결과처리법
대한지질학회 학술대회
2015 .10
-
해산로티퍼 (Brachionus plicatilis)의 생존 및 개체군 성장률을 이용한 중금속 (As, Cr, Pb) 독성평가
환경생물
2016 .01
-
Poly(p-phenylene terephthalamide) oligomers analysis using direct Infusion-mass spectrometry (DI-MS)
한국분석과학회 학술대회
2018 .05
-
SHRIMP U-Pb 저어콘 연대측정 최적 분석조건 연구
한국암석학회 학술발표회 논문집
2015 .05
-
Cs-, Sr-, Cd-, Pb-로 치환된 합성 모데나이트의 결정구조 비교 연구
한국암석학회 학술발표회 논문집
2023 .06
-
Cs-, Sr-, Cd-, Pb-로 치환된 합성 모데나이트의 결정구조 비교 연구
대한지질학회 학술대회
2023 .11
-
PDMS (Polydimethylsiloxane) stamping: 동물세포의 PDMS oligomer 단일 고분자 적층 깊이 및 패턴 인지 한계 연구
한국분석과학회 학술대회
2023 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0