지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Analysis Health and Toxicology Vol.34 No.3
- 발행연도
- 2019.9
- 수록면
- 11 - 14 (4page)
이용수
초록· 키워드
오류제보하기
Benzalkonium chloride is a cationic surfactant widely used as a disinfectant, preservative, and sanitizer in many public places as well as domestically. The purpose of this study is to compare the acute toxicity of lethal doses (LDx) and the target organs after intratracheal instillation and oral ingestion by mice, which is a preliminary test prior to the repeated dose toxicity test. When Balb/c mice were treated with a single dose of benzalkonium chloride via oral administration, LD50 was 241.7 ㎎/㎏. However, it was comparatively decreased to 8.5 ㎎/㎏ following intratracheal treatment, which suggests that lung may be the main target of toxicity. Although the histopathology showed inflammatory responses in the lung after intratracheal instillation, it still did not confirm that the inflammatory responses were the key factors inducing death in the treated animal. Acute and fatal mechanisms such as bronchoconstriction or neurotoxicity associated with benzalkonium chloride exposure should be further investigated.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effects of 2-week repeated intratracheal instillation of vehicles on mice lung
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Assessment of the lung toxic effect of whole cigarette smoke extract on repeated intratracheal instillation
한국실험동물학회 학술발표대회 논문집
2022 .07
-
폴리에틸렌 미세플라스틱의 임신 마우스 위내 투여 및 기도 점적에 따른 신생자 간독성 평가
한국환경보건학회지
2022 .04
-
CPC의 기관내점적 실험을 통한 랫드의 호흡기 영향 평가
환경독성보건학회 심포지엄 및 학술대회
2017 .10
-
Biodistribution study of microplastics in mouse following intratracheal instillation by PET/CT
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Identification for Asbestos bodies in the Lung tissues of Syrian hamster after Intratracheal Instillation of Asbestos
대한직업환경의학회 학술대회 논문집
2015 .11
-
SWCNT 및 MWCNT의 기관내 점적주입 후 폐 계면활성제의 분석
한국환경보건학회지
2017 .08
-
The toxicity evaluation of cement and nano-cement after intratracheal instillation to rat
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Interaction of Benzalkonium chloride with bovine serum albumin: spectroscopic study and activity assay
환경독성보건학회 심포지엄 및 학술대회
2019 .10
-
Evaluation of the effects of intratracheal instillation of polyhexamethylene guanidine-phosphate (PHMG-p) on pregnancy and fetal outcomes in rats
환경독성보건학회 심포지엄 및 학술대회
2023 .11
-
Acute and sub-acute oral toxicity study of multi-mineral compound in rats
한국실험동물학회 학술발표대회 논문집
2019 .07
-
Anti-inflammatory Role of Mesenchymal Stem Cells in an Acute Lung Injury Mouse Model
Acute and Critical Care
2018 .01
-
Single oral dose toxicity test of DMZ-33, 71 and 77 in Balb/c mice
한국실험동물학회 학술발표대회 논문집
2022 .01
-
Dysfunction of female reproductive system is caused by exposure to airborne nanoplatics in mice
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Histopathological changes in the lungs of rats instilled with Korean chrysotile
Environmental Analysis Health and Toxicology
2021 .09
-
Estimation of dermal exposure to residual benzalkonium chlorides after table disinfection
환경독성보건학회 심포지엄 및 학술대회
2023 .11
-
Inhalation toxicity study of benzalkonium chloride that is one of the substances causing humidifier disinfection in rats
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Acute pulmonary toxicity and inflammation induced by the mixtures of household chemicals in rats
한국실험동물학회 학술발표대회 논문집
2015 .02
-
Development of a LC-MS/MS method to measure dermal migration of the residual COVID19 disinfectant Benzalkonium chloride from different surfaces
환경독성보건학회 심포지엄 및 학술대회
2022 .05
-
제형별 살균소독제와 함유 주요성분인 Benzalkonium chloride가 zebrafish embryo에 미치는 독성 영향
환경독성보건학회 심포지엄 및 학술대회
2021 .10
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0