지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Atorvastatin is one of the most widely prescribed medications for dyslipidemia treatment. In Korea, post combined therapy with ezetimibe, a 73-year-old woman was reported by a community pharmacy to have experienced visual field defect, which recovered after drug discontinuation. She had never experienced this symptom before, and several studies have reported an association between use of statins and visual disorders such as blurred vision, diplopia, and cataract. Blockage of cholesterol accumulation, oxidative stress, or myopathy is expected to be a cause of this symptom. Naranjo scale, Korean causality assessment algorithm (Ver.2), and World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria were the three tools used to determine causality between the visual disorder and atorvastatin. The results represent ‘probable’, ‘certain’, and ‘probable/likely’ causality, respectively. Our results, in combination with a review of literature, indicate that ocular adverse effects are highly likely related to atorvastatin
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
DrugStats Database. Atorvastatin, Drug Usage Statistics, United States, 2006-2016 / ClinCalc.com
Korean Index of Medical Specialties / Atorvastatin
Lee SH / 2012 / Effect of atorvastatin monotherapy and low-dose atorvastatin/ezetimibe combination on fasting and postprandial triglycerides in combined hyperlipedemia / J Cardiovasc Pharmacol Ther 17(1):65~71
Ballantyne CM / 2003 / Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial / Circulation 107(19):2409~2415
Mizranita V / 2015 / Statin-associated ocular disorders: the FDA and ADRAC data / Int J Clin Pharm 37(5):844~850
Korean Index of Medical Specialties / Atorvastatin
Lee SH / 2012 / Effect of atorvastatin monotherapy and low-dose atorvastatin/ezetimibe combination on fasting and postprandial triglycerides in combined hyperlipedemia / J Cardiovasc Pharmacol Ther 17(1):65~71
Ballantyne CM / 2003 / Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial / Circulation 107(19):2409~2415
Mizranita V / 2015 / Statin-associated ocular disorders: the FDA and ADRAC data / Int J Clin Pharm 37(5):844~850
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