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산약 에탄올 추출물의 항염 및 항주름 효과 연구
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Study of Effects of Discorea japonica Thunb Ethanol Extract on Anti-inflammation and Anti-wrinkle

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자료유형
학술저널
저자정보
저널정보
한국미용학회 한국미용학회지 한국미용학회지 제25권 제4호 KCI Accredited Journals
발행연도
2019.1
수록면
947 - 954 (8page)

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산약 에탄올 추출물의 항염 및 항주름 효과 연구
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Inulae Flower (山藥, Dioscorea japonica Thunb., Inulae Flos) refers to a dried head flower of elecampane (Dioscorea japonica Thunb. Var japonica), a medical herb pertaining to Inula Linne and it is typically called elecampane (山藥) in oriental medicine. It tastes sweet a little bit or plain and slightly warm, and is known to have medical effects such as chronic enteritis, chronic nephritis. It includes saponin, musine, choline, glycoprotein, and is rich in amino acids. This study was carried out to examine the effects of anti-inflammation and anti-wrinkle, aming to provide natural ingredients for functional cosmetic products. EtOAc fraction of Inulae flower extract was examined to find out the inhibition activity on Nitric Oxide (NO), cytokine IL-1β, IL-6, and TNF-α. The inhibition activity of Nitric Oxide (NO) to find out the anti-inflammatory activity of Inulae flower extracts discovered that control ability showed 100% at 50 μg/ml concentration and it was confirmed excellent. It was also found that it controls the creation or secretion of cytokine IL-1β, IL-6, and TNF-α, thus used as ingredients for functional cosmetic products such as products effective for anti-inflammation. An analysis of MMP-1, a standard for anti-wrinkle, expression control effects from Inulae flower extracts observed that its extracts had approximately 58.2% control effects at 25 μg/ml concentration and it had effects for enhancing skin wrinkles.

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