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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Sporotrichosis is a common deep mycosis caused by the Sporothrix schenckii complex. Until 2016, no molecular studies had been conducted on these fungi, and all the included strains were reported as S. schenckii. However, investigations conducted in northeast China, Japan, and India revealed that S. globosa was the most prevalent Sporothrix species, whereas S. schenckii sensu stricto was reported very rarely. Objective: To investigate the accurate prevalent causative species of sporotrichosis among strains reported as S. schenckii in Korea. Methods: We isolated strains of Sporothrix spp. Prevalent in Korea from fungus collection centers or private collections and reviewed the available literature on molecular studies of strains from this region. We found five S. schenckii (1998-2016) and three S. globosa (2016-2018) strains. Ribosomal DNA internal transcribed spacer (ITS) sequences of these strains were compared with those of the S. schenckii complex strains. Results: The ribosomal ITS sequences of the eight strains were 100% identical with that of S. globose. No S. schenckii sensu stricto was found. In addition, a study on the molecular analysis of Korean S. schenckii published by Ishizaki et al. (2004) demonstrated that the eight strains were of the mitochondrial subtype group B (S. globosa). Thus, all the 16 strains examined within the Korean S. schenckii complex were determined to be S. globosa. Conclusion: In summary, S. globosa is the causative species within the tested Korean sporotrichosis cases reported between 1998 and 2018. Based on our analyses, S. globosa, and not S. schenckii, may be the predominant species in Korea.
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참고문헌 (48)
참고문헌 신청
Rippon JW. / 1988 / Medical mycology: the pathogenic fungi and the pathogenic actinomycetes / WB Saunders :325~328
Marimon R / 2007 / Sporothrix brasiliensis, S. globosa and S. mexicana, three new Sporothrix species of clinical interest / J Clin Microbiol 45:3198~3206
shizaki H / 2000 / Molecular epidemiology of Sporothrix schenkii / Nihon Ishinkin Gakkai Zasshi 41:245~249
Liu TT / 2014 / Molecular identification of Sporothrix clinical isolates in China / J Zhejiang Univ Sci B 15:100~108
Yu X / 2013 / Phenotypic and molecular identification of Sporothrix isolates of clinical origin in northeast China / Mycopathologia 176:67~74
Marimon R / 2007 / Sporothrix brasiliensis, S. globosa and S. mexicana, three new Sporothrix species of clinical interest / J Clin Microbiol 45:3198~3206
shizaki H / 2000 / Molecular epidemiology of Sporothrix schenkii / Nihon Ishinkin Gakkai Zasshi 41:245~249
Liu TT / 2014 / Molecular identification of Sporothrix clinical isolates in China / J Zhejiang Univ Sci B 15:100~108
Yu X / 2013 / Phenotypic and molecular identification of Sporothrix isolates of clinical origin in northeast China / Mycopathologia 176:67~74
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