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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제53권 제2호
- 발행연도
- 2019.1
- 수록면
- 125 - 128 (4page)
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초록· 키워드
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Type 1 autoimmune pancreatitis (AIP1) is an IgG4-related systemic disease that mimics tumors. We report a rare case of AIP1 accompanied by mucinous cystic neoplasm (MCN). A pancreatic lesion was incidentally detected in a woman in her 60s. After 6 years of follow-up, the lesion abruptly increased in size. Computed tomography showed a 3.5 cm unilocular cyst in the tail of the pancreas and distal pancreatectomy was performed. On microscopic examination, the cyst was lined by mucinous and non-mucinous epithelial cells with mild cytologic atypia. The surrounding stroma comprised ovarian-type spindle cells with progesterone receptor positivity. The pericystic pancreas exhibited multifocal lymphoid follicles, lymphoplasmacytic infiltrations, obliterative phlebitis, and storiform fibrosis. IgG4-positive plasma cell infiltration (215 cells high-power field) and the IgG4/IgG ratio (57%) were increased. Cases of MCN coexisting with AIP1 are extremely rare; only two such cases have been reported in the English-language literature. This third case featured low-grade MCN with AIP1.
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등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Bosman FT / 2010 / WHO classification of tumours of the digestive system / International Agency for Research on Cancer
Basturk O / 2015 / A revised classification system and recommendations from the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas / Am J Surg Pathol 39:1730~1741
Hong SM / 2011 / Molecular signatures of pancreatic cancer / Arch Pathol Lab Med 135:716~727
Hruban RH / 2007 / AFIP atlas of tumor pathology, series IV. Tumors of the pancreas / Armed Forces Institute of Pathology
Hart PA / 2015 / Recent advances in autoimmune pancreatitis / Gastroenterology 149:39~51
Basturk O / 2015 / A revised classification system and recommendations from the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas / Am J Surg Pathol 39:1730~1741
Hong SM / 2011 / Molecular signatures of pancreatic cancer / Arch Pathol Lab Med 135:716~727
Hruban RH / 2007 / AFIP atlas of tumor pathology, series IV. Tumors of the pancreas / Armed Forces Institute of Pathology
Hart PA / 2015 / Recent advances in autoimmune pancreatitis / Gastroenterology 149:39~51
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