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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제17권 제3호
- 발행연도
- 2019.1
- 수록면
- 409 - 414 (6page)
이용수
초록· 키워드
오류제보하기
Objective: The present study aimed to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) at a high frequency using a miniaturized device compared to standard rTMS and sham rTMS for the treatment of depression. Methods: Fifty-four patients with depression were randomly assigned to either 15 days of miniaturized, standard, or sham rTMS. The stimulation consisted of 60 trains of 5 seconds at 10 Hz for 30 minutes. Clinical measures were assessed at baseline and on the final day of the stimulation. Results: A repeated-measures analysis of variance revealed a significant main effect of time and a time by group interaction on Hamilton Rating Scale for Depression scores. There were no significant correlations between individual motor thresholds and changes of clinical outcomes. Our results revealed a significant reduction in the Hamilton Rating Scale for Depression in the miniaturized and standard groups compared to the sham group. Conclusion: The antidepressant utility of miniaturized rTMS using subthreshold stimulation was comparable to that of standard stimulation.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Olfson M / 2002 / National trends in the outpatient treatment of depression / JAMA 287:203~209
George MS / 2010 / Noninvasive techniques for probing neurocircuitry and treating illness : vagus nerve stimulation(VNS), transcranial magnetic stimulation(TMS)and transcranial direct current stimulation(tDCS) / Neuropsychopharmacology 35:301~316
Pascual-Leone A / 1996 / Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression / Lancet 348:233~237
Padberg F / 2009 / Repetitive transcranial magnetic stimulation of the prefrontal cortex in depression / Exp Neurol 219:2~13
George MS / 1995 / Daily repetitive transcranial magnetic stimulation(rTMS)improves mood in depression / Neuroreport 6:1853~1856
George MS / 2010 / Noninvasive techniques for probing neurocircuitry and treating illness : vagus nerve stimulation(VNS), transcranial magnetic stimulation(TMS)and transcranial direct current stimulation(tDCS) / Neuropsychopharmacology 35:301~316
Pascual-Leone A / 1996 / Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression / Lancet 348:233~237
Padberg F / 2009 / Repetitive transcranial magnetic stimulation of the prefrontal cortex in depression / Exp Neurol 219:2~13
George MS / 1995 / Daily repetitive transcranial magnetic stimulation(rTMS)improves mood in depression / Neuroreport 6:1853~1856
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