지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background and Purpose Thrombectomy within 24 hours can improve outcomes in selected patients with a clinical-infarct mismatch. We devised an easy-to-use visual estimation tool that allows infarct volume estimation in centers with limited resources. Methods We identified 1,031 patients with cardioembolic or large-artery atherosclerosis infarction on diffusion-weighted images (DWIs) obtained before recanalization therapy and within 24 hours of onset, and occlusion of the internal carotid or middle cerebral artery. Acute DWIs were mapped onto a standard template and used to create visual reference maps with known lesion volumes, which were then used in a validation study (with 130 cases) against software estimates of infarct volume. Results The DWI reference map chart comprises 144 maps corresponding to 12 different infarct volumes (0.5, 1, 2, 3, 5, 7, 9, 11, 13, 15, 17, and 19 mL) in each of 12 template slices (Montreal Neurological Institute z-axis –15 to 51 mm). Infarct volume in a patient is estimated by selecting a slice with a similar infarct size at the corresponding z-axis level on the reference maps and then adding up over all slices. The method yielded good correlations to software volumetrics and was easily learned by both experienced and junior physicians, with approximately 1 to 2 minutes spent per case. The sensitivity, specificity, and accuracy for detecting threshold infarct volumes (<21, <31, and <51 mL) were very high (all about >90%). Conclusions We developed easy-to-use reference maps that allow prompt and reliable visual estimation of infarct volumes for triaging patients to thrombectomy in acute stroke.
목차
등록된 정보가 없습니다.
참고문헌 (11)
참고문헌 신청
Nogueira RG / 2018 / Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct / N Engl J Med 378:11~21
Keon-Joo Lee / 2018 / Nationwide Estimation of Eligibility for Endovascular Thrombectomy Based on the DAWN Trial / 대한뇌졸중학회지 20(2):277~279
Ryu WS / 2014 / Grading and interpretation of white matter hyperintensities using statistical maps / Stroke 45:3567~3575
Ryu WS / 2017 / Stroke outcomes are worse with larger leukoaraiosis volumes / Brain 140:158~170
Kim DE / 2019 / Mapping the supratentorial cerebral arterial territories using 1160 large artery infarcts / JAMA Neurol 76:72~80
Keon-Joo Lee / 2018 / Nationwide Estimation of Eligibility for Endovascular Thrombectomy Based on the DAWN Trial / 대한뇌졸중학회지 20(2):277~279
Ryu WS / 2014 / Grading and interpretation of white matter hyperintensities using statistical maps / Stroke 45:3567~3575
Ryu WS / 2017 / Stroke outcomes are worse with larger leukoaraiosis volumes / Brain 140:158~170
Kim DE / 2019 / Mapping the supratentorial cerebral arterial territories using 1160 large artery infarcts / JAMA Neurol 76:72~80
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