지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.97 No.4
- 발행연도
- 2019.10
- 수록면
- 202 - 209 (8page)
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초록· 키워드
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Purpose: We aimed to compare clinical outcomes after carotid endarterectomy (CEA) between Korean patients with and without severe contralateral extracranial carotid stenosis or occlusion (SCSO).
Methods: Between January 2004 and December 2014, a total of 661 patients who underwent 731 CEAs were stratified by SCSO (non-SCSO and SCSO groups) and analyzed retrospectively. The study outcomes included the occurrence of major adverse cardiovascular events (MACE), defined as stroke or myocardial infarction, and all-cause mortality during the perioperative period and within 4 years after CEA.
Results: There were no significant differences in the incidence of MACE or any individual MACE manifestations between the 2 groups during the perioperative period or within 4 years after CEA. On multivariate analysis to identify clinical variables associated with long-term study outcomes, older age (hazard ratios [HRs], 1.06; 95% confidence intervals [CIs], 1.03–1.09; P < 0.001) and diabetes mellitus (HR, 1.71; 95% CI, 1.14–2.57; P = 0.010) were significantly associated with an increased risk of MACE occurrence, while preexisting SCSO was not associated with long-term incidence of MACE and individual MACE components. Kaplan-Meier survival analysis showed similar MACE-free (P = 0.509), overall (P = 0.642), and strokefree (P = 0.650) survival rates in the 2 groups.
Conclusion: There were no significant differences in MACE incidence after CEA between the non-SCSO and SCSO groups, and preexisting SCSO was not associated with an increased risk of perioperative or long-term MACE occurrence.
Methods: Between January 2004 and December 2014, a total of 661 patients who underwent 731 CEAs were stratified by SCSO (non-SCSO and SCSO groups) and analyzed retrospectively. The study outcomes included the occurrence of major adverse cardiovascular events (MACE), defined as stroke or myocardial infarction, and all-cause mortality during the perioperative period and within 4 years after CEA.
Results: There were no significant differences in the incidence of MACE or any individual MACE manifestations between the 2 groups during the perioperative period or within 4 years after CEA. On multivariate analysis to identify clinical variables associated with long-term study outcomes, older age (hazard ratios [HRs], 1.06; 95% confidence intervals [CIs], 1.03–1.09; P < 0.001) and diabetes mellitus (HR, 1.71; 95% CI, 1.14–2.57; P = 0.010) were significantly associated with an increased risk of MACE occurrence, while preexisting SCSO was not associated with long-term incidence of MACE and individual MACE components. Kaplan-Meier survival analysis showed similar MACE-free (P = 0.509), overall (P = 0.642), and strokefree (P = 0.650) survival rates in the 2 groups.
Conclusion: There were no significant differences in MACE incidence after CEA between the non-SCSO and SCSO groups, and preexisting SCSO was not associated with an increased risk of perioperative or long-term MACE occurrence.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (29)
참고문헌 신청
Ueshima H / 2008 / Cardiovascular disease and risk factors in Asia : a selected review / Circulation 118:2702~2709
Jee SH / 1999 / Smoking and atherosclerotic cardiovascular disease in men with low levels of serum cholesterol : the Korea Medical Insurance Corporation Study / JAMA 282:2149~2155
Brott TG / 2010 / Stenting versus endarterectomy for treatment of carotid-artery stenosis / N Engl J Med 363:11~23
Silver FL / 2011 / Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial(CREST) / Stroke 42:675~680
North American Symptomatic Carotid Endarterectomy Trial Collaborators / 1991 / Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis / N Engl J Med 325:445~453
Jee SH / 1999 / Smoking and atherosclerotic cardiovascular disease in men with low levels of serum cholesterol : the Korea Medical Insurance Corporation Study / JAMA 282:2149~2155
Brott TG / 2010 / Stenting versus endarterectomy for treatment of carotid-artery stenosis / N Engl J Med 363:11~23
Silver FL / 2011 / Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial(CREST) / Stroke 42:675~680
North American Symptomatic Carotid Endarterectomy Trial Collaborators / 1991 / Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis / N Engl J Med 325:445~453
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