메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류
인문학
인문학 일반 역사학 철학 종교학 어문학 기타 인문학
사회과학
사회과학 일반 경영학 관광학 교육학 군사학 문헌정보학 법학 사회학 신문방송학 심리과학 정치외교학 지리학 행정학 경제학 무역학 인류학 기타 사회과학
자연과학
자연과학 일반 물리학 생물학 생활과학 수학·통계학 천문학 지구과학 화학 기타 자연과학
공학
공학 일반 건축공학 기계공학 산업공학 재료·에너지공학 전기전자공학 조선해양공학 화학공학 컴퓨터학 기타공학
의약학
의학 일반 간호학 수의학 약학 한의학 기초의학 임상의학 기타 의약학
농수해양학
농수해양학 일반 농학 수산학 식품과학 임학 축산학 해상운송학 기타 농수해양학
예술체육학
예술 일반 디자인 미술 미용 사진 음악학 의상 체육 공연매체예술 기타 예술체육학
복합학
학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

ENG

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제53권 제4호
발행연도
2012.1
수록면
801 - 805 (5page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Purpose: Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). Animal models of knee OA have shown that sensory nerve fibers innervating the knee are significantly damaged with destruction of subchondral bone junction, and induce neuropathic pain (NP). Our objective was to examine NP in the knees of OA patients using painDETECT (an NP questionnaire) and to evaluate the relationship between NP, pain intensity, and stage of OA. Materials and Methods:Ninety-two knee OA patients were evaluated in this study. Pain scores using Visual Analogue Scales (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), painDETECT, duration of symptoms, severity of OA using the Kellgren-Lawrence (KL) system, and amount of joint fluid were evaluated and compared using a Spearman’s correlation coefficient by rank test. Results: Our study identified at least 5.4% of our knee OA patients as likely to have NP and 15.2% as possibly having NP. The painDETECT score was significantly correlated with the VAS and WOMAC pain severity. Compared with the painDETECT score, there was a tendency for positive correlation with the KL grade, and tendency for negative correlation with the existence and amount of joint fluid, but these correlations were not significant. Conclusion: PainDETECT scores classified 5.4% of pain from knee OA as NP. NP tended to be seen in patients with less joint fluid and increased KL grade, both of which corresponded to late stages of OA. It is important to consider the existence of NP in the treatment of knee OA pain.
#Knee #osteoarthritis #neuropathic pain #nociceptive pain

목차

등록된 정보가 없습니다.

참고문헌 (1)

참고문헌 신청
Centers for Disease Control and Prevention / / Arthritis types: overview | 2. [학술지(정기간행물)] - Daousi C / 2004 / Chronic painful peripheral neuropathy in an urban community: a controlled comparison of people with and without diabetes / Diabet Med 21 : 976 ~ 982 | 3. [학술지(정기간행물)] - Siddall PJ / 2003 / A longitudinal study of the prevalence and characteristics of pain in the first 5 years following spinal cord injury / Pain 103 : 249 ~ 257 | 4. [학술지(정기간행물)] - van der Kraan PM / 1989 / Development of osteoarthritic lesions in mice by “metabolic” and “mechanical” alterations in the knee joints / Am J Pathol 135 : 1001 ~ 1014 | 5. [학술지(정기간행물)] - Ochiai N / 2007 / Extracorporeal shock wave therapy improves motor dysfunction and pain originating from knee osteoarthritis in rats / Osteoarthritis Cartilage 15 : 1093 ~ 1096 | 6. [학술지(정기간행물)] - Ivanavicius SP / 2007 / Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation / Pain 128 : 272 ~ 282 | 7. [학술지(정기간행물)] - Fernihough J / 2004 / Pain related behaviour in two models of osteoarthritis in the rat knee / Pain 112 : 83 ~ 93 | 8. [학술지(정기간행물)] - Pomonis JD / 2005 / Development and pharmacological characterization of a rat model of osteoarthritis pain / Pain 114 : 339 ~ 346 | 9. [학술지(정기간행물)] - Freynhagen R / 2006 / painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain / Curr Med Res Opin 22 : 1911 ~ 1920 | 10. [학술지(정기간행물)] - Bennett M / 2001 / The LANSS Pain Scale: the Leeds assessment of neuropathic symptoms and signs / Pain 92 : 147 ~ 157 | 11. [학술지(정기간행물)] - Bouhassira D / 2005 / Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4) / Pain 114 : 29 ~ 36 | 12. [학술지(정기간행물)] - Portenoy R. / 2006 / Development and testing of a neuropathic pain screening questionnaire: ID Pain / Curr Med Res Opin 22 : 1555 ~ 1565 | 13. [학술지(정기간행물)] - Krause SJ / 2003 / Development of a neuropathic pain questionnaire / Clin J Pain 19 : 306 ~ 314 | 14. [학술지(정기간행물)] - Bennett MI / 2007 / Using screening tools to identify neuropathic pain / Pain 127 : 199 ~ 203 | 15. [학술지(정기간행물)] - Hochman JR / 2010 / The nerve of osteoarthritis pain / Arthritis Care Res 62 : 1019 ~ 1023 | 16. [학술지(정기간행물)] - Bellamy N / 1988 / Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee / J Rheumatol 15 : 1833 ~ 1840 | 17. [학술지(정기간행물)] - Kellgren JH / 1957 / Lawrence JS. Radiological assessment of osteo-arthrosis / Ann Rheum Dis 16 : 494 ~ 502 | 18. [학술지(정기간행물)] - Mäntyselkä P / 2001 / Pain as a reason to visit the doctor: a study in Finnish primary health care / Pain 89 : 175 ~ 180 | 19. [학술지(정기간행물)] - Grönblad M / 1985 / Innervation of synovial membrane and meniscus / Acta Orthop Scand 56 : 484 ~ 486 | 20. [학술지(정기간행물)] - Fortier LA / 1997 / Distributional changes in substance P nociceptive fiber patterns in naturally osteoarthritic articulations / J Rheumatol 24 : 524 ~ 530 | 21. [학술지(정기간행물)] - Saito T / 2000 / Distribution of neuropeptides in synovium of the knee with osteoarthritis / Clin Orthop Relat Res : 172 ~ 182 | 22. [학술지(정기간행물)] - Suri S / 2007 / Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis / Ann Rheum Dis 66 : 1423 ~ 1428 | 23. [학술지(정기간행물)] - Ogino S / 2009 / Higashi M, et al. Detection of pain-related molecules in the subchondral bone of osteoarthritic knees / Clin Rheumatol 28 : 1395 ~ 1402 | 24. [학술지(정기간행물)] - Creamer P / 1996 / Pain mechanisms in osteoarthritis of the knee: effect of intraarticular anesthetic / J Rheumatol 23 : 1031 ~ 1036 | 25. [학술지(정기간행물)] - Ethgen O / 2004 / Health-related quality of life in total hip and total knee arthroplasty. A qualitative and systematic review of the literature / J Bone Joint Surg Am 86 (A) : 963 ~ 974 | 26. [학술지(정기간행물)] - Kosek E / 2000 / Lack of pressure pain modulation by heterotopic noxious conditioning stimulation in patients with painful osteoarthritis before, but not following, surgical pain relief / Pain 88 : 69 ~ 78 google schola

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0