지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
- Many alternative biocidal additives were applied to antifouling paint to replace TBT,and Sea-Nine 211 is one of alternating organic booster compounds used in antifouling paint. Inthis study, extent of Sea-Nine 211 toxicity on marine benthic bivalve is evaluated.Sea-Nine 211 was injected to Surf clam, Pseudocardium sachalinensis, that inhabitate northernpart of Gangwon Province, Korea. Survival rate of the clam and xenobiotics metabolizing enzymeactivities in digestive gland were measured during 4 day-exposure period. The results were com-pared with those of TBT exposed clam. There were no mortality of clam in the solvent (DMSO)control group and the three Sea-Nine 211 exposure groups(5, 25, 50 mg kg-1 body weight), whilethe clam exposed to 1, 2 and 5 mg kg-1 TBT chloride (TBTC) demonstrated 70, 30 and 0% sur-vival rate, respectively. The Sea-Nine 211 exposure group showed a tendency of cytochrome P450(CYP) induction according to the exposure duration, on the other hand, CYP content was decr-eased in the TBT exposure group. NADPH cytochrome P450 reductase activity slightly increaseaccording to the exposure duration in the Sea-Nine 211 exposure group, while TBTC inhibit itsactivity as CYP content. Moreover, there was no significant change of NADH cytochrome b5 re-ductate activity in the clam epxosed to Sea-Nine 211. In the TBTC exposure group, its activity in-creased in early exposure period and then significantly decreased the rest of exposure period.All the results indicate that Sea-Nine 211 demonstrated a tendency to induce CYP level, whileTBTC inhibits the CYP level, NADPH cytochrome P450 reductase and NADH cytochrome b5reductase activities.
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참고문헌 (24)
참고문헌 신청
Alzieu C. / 1991 / Environmental problems caused by TBT in France: Assessment, regulations, prospects / Mar. Environ. Res 32 : 7 ~ 17
Beaumont AR / 1984 / High mortality of the larvae of the common mussel at low concentrations of tributyltin / Mar. Poll. Bull 15 : 402 ~ 405
Chambers JE / 1976 / Xenobiotic biotransformation in fish / Comp. Biochem. Physiol 55C : 77 ~ 84
Davies IM / 1988 / Effects of tributyltin compounds from antifoulants on Pacific oysters (Crassostrea gigas) in Scottish sea lochs / Aquaculture 74 : 319 ~ 330
De Nys / 1996 / The need for standardized broad scale bioassay testing: a case study using the red algae Laurencia rigida / Biofouling 10 : 213 ~ 224
Beaumont AR / 1984 / High mortality of the larvae of the common mussel at low concentrations of tributyltin / Mar. Poll. Bull 15 : 402 ~ 405
Chambers JE / 1976 / Xenobiotic biotransformation in fish / Comp. Biochem. Physiol 55C : 77 ~ 84
Davies IM / 1988 / Effects of tributyltin compounds from antifoulants on Pacific oysters (Crassostrea gigas) in Scottish sea lochs / Aquaculture 74 : 319 ~ 330
De Nys / 1996 / The need for standardized broad scale bioassay testing: a case study using the red algae Laurencia rigida / Biofouling 10 : 213 ~ 224
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