지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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This study was carried out to investigate the effects of pycnogenol (PYC) on the cutaneous wound healing of the mice. The wounds were extracted on days 1, 3, 5, and 7 post-injury for histomorphometrical analysis including wound area, infiltrating inflammatory cells, wound contracture including collagen deposition. As the result, the wound area of PYC-treated group was larger than the control group on days 1 to 7. Inflammatory cells in the PYC-treated wounds were decreased at day 1 compared to the control wound tissue. From day 3 to 7, there was no significant difference between the control and the PYC-treated skin wounds. Though the degree of contraction in the PYC-treated group was lower than that of the control group from days 1 to 5, but appeared significantly higher on day 7. Compared to the control group, collagen accumulation in the PYC-treated group was higher than that of the control group from days 5 to 7. From this result, it may support the possibility that PYC would be useful agent for early inflammatory response and matrix remodeling phase of the skin wounds.
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참고문헌 (24)
참고문헌 신청
Babior B M / 2000 / Phagocytes and oxidative stress / Am. J. Med 109 : 33 ~ 44
Berryman A M / 2004 / Influence of treatment of diabetic rats with combinations of pycnogenol, beta-carotene, and alpha-lipoic acid on parameters of oxidative stress / J. Bio
Blazso G / 1997 / Anti-inflammatory activities of procyanidin containing extracts from Pinus pinaster Ait. after oral and cutaneous application / Pharmazie 52 : 380 ~ 382
Blazso G / 2004 / Pycnogenol accelerates wound healing and reduces scar formation / Phytother. Res 18 : 579 ~ 581
Chida M / 1999 / In vitro testing of antioxidants and biochemical end-point in bovine retinal tissue / Ophthalmic Res 31 : 407 ~ 415
Berryman A M / 2004 / Influence of treatment of diabetic rats with combinations of pycnogenol, beta-carotene, and alpha-lipoic acid on parameters of oxidative stress / J. Bio
Blazso G / 1997 / Anti-inflammatory activities of procyanidin containing extracts from Pinus pinaster Ait. after oral and cutaneous application / Pharmazie 52 : 380 ~ 382
Blazso G / 2004 / Pycnogenol accelerates wound healing and reduces scar formation / Phytother. Res 18 : 579 ~ 581
Chida M / 1999 / In vitro testing of antioxidants and biochemical end-point in bovine retinal tissue / Ophthalmic Res 31 : 407 ~ 415
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