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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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This study was conducted to analyze the cost-utility of ramosetron monotherapy, trimebutine monotherapy and trimebutine+loperamide combination therapy in male diarrhea-predominant patients with irritable bowel syndrome (IBS) in Korean healthcare setting. We constructed a decision-analytical model to estimate both total costs for each state of health and outcomes such as IBS-symptoms improvement for 3 and 6 months time horizon. Base analysis found that for ramosetron treatment with the price of KW910 for 5 μg tablet, incremental cost effectiveness ratios (ICERs, cost per quality-adjusted life day) were KW85,000 and KW62,000 for 3 months and 6 months, respectively, compared with trimebutine.
But ramosetron was a dominant strategy when compared with trimebutine+loperamide for both 3 months and 6 months. Sensitivity analyses showed robust results for drug acquisition costs till ramosetron price of KW950/tablet. In conclusion, ramosetron was a cost-effective regimen compared with trimebutine or trimebutine+loperamide from the societal perspective.
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참고문헌 (26)
참고문헌 신청
/ / International Statistical Classification of Diseases and Related Health Problems 10th Revision
/ 2009 / IMS data MAT 06/2009
Agrawal A / 2006 / Irritable bowel syndrome: diagnosis and management / BMJ 332 : 28083 ~
Akehurst RL / 2002 / Health-related quality of life and cost impact of irritable bowel syndrome in a UK primary care setting / Pharmacoeconomics 20 (7) : 455 ~ 462
Astellas Report / 2006 / YM060 - 장기투여시험 총괄보고서
/ 2009 / IMS data MAT 06/2009
Agrawal A / 2006 / Irritable bowel syndrome: diagnosis and management / BMJ 332 : 28083 ~
Akehurst RL / 2002 / Health-related quality of life and cost impact of irritable bowel syndrome in a UK primary care setting / Pharmacoeconomics 20 (7) : 455 ~ 462
Astellas Report / 2006 / YM060 - 장기투여시험 총괄보고서
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