지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
The purpose of this study was to evaluate the clinical efficacy of a standardized special ethanol extract from Gynostemma pentaphyllum as a management for anxiety and stress of normal population. This is a two-arm, parallelgroup,randomized, double blind clinical trial comparing Gynostemma pentaphyllum extract 200 mg bid (GP-EX, n=48)or placebo bid (n=54). The main outcome measures were the decrease in anxiety sensitivity index (ASI), the State version (S-STAI) of the Stait-Trait Anxiety Inventory (STAI) and the Trait version (T-STAT) of the STAI from baseline over a 6 weeks treatment period. In more anxious group (S-STAI50 or ASI19), the anxiety in group with GP-EX was decreased significantly than one in normal population with placebo [S-STAI50: T-STAI = from 57.7 ± 6.5 (mean ±S.D.) to 46.8 ± 11.2 in normal population with GP-EX, p=0.002 vs. from 54.1 ± 9.9 to 49.0 ± 9.6 in normal population with placebo, p>0.05; ASI19: T-STAI = from 47.2 ± 12.0 to 42.4 ± 11.1 in normal population with GP-EX,p=0.022 vs. from 48.7 ± 11.5 to 46.0 ± 10.4 in normal population with placebo, p>0.05]. The most frequently reported adverse reactions considered possibly related to treatment were mild gastrointestinal events. GP-EX is more effective than placebo and is well tolerated as a therapy for anxiety and stress of normal population.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Attawish A / 2004 / Chronic toxicity of Gynostemma pentaphyllum / Fitoterapia 75 : 539 ~ 551
Bieling PJ / 1998 / The State-Trait Anxiety Inventory, Trait version: structure and content reexamined / Behav Res Ther 36 (7) : 777 ~ 788
Blumert A / 1999 / Jiagulan, China's immortality herb / Torchlight Publishing : 66 ~ 71
Bohlmeijer E / 2010 / The effects of mindfulness-based stress reduction therapy on mental health of adults with a chronic medical disease: a metaanalysis / J Psychosom Res 6
Clark LA / 1991 / Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications / J Abnorm Psychol 100 (3) : 316 ~ 336
Bieling PJ / 1998 / The State-Trait Anxiety Inventory, Trait version: structure and content reexamined / Behav Res Ther 36 (7) : 777 ~ 788
Blumert A / 1999 / Jiagulan, China's immortality herb / Torchlight Publishing : 66 ~ 71
Bohlmeijer E / 2010 / The effects of mindfulness-based stress reduction therapy on mental health of adults with a chronic medical disease: a metaanalysis / J Psychosom Res 6
Clark LA / 1991 / Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications / J Abnorm Psychol 100 (3) : 316 ~ 336
이 논문의 저자 정보
최근 본 자료
댓글(0)
0