지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
The most common complication after liver transplantation (LT) is bacterial infection. The incidence of surgical site infections (SSIs) after LT was variable from 8.8%~37%. However, there has been no confirmed guideline in use of prophylactic antibiotics after LT. Ampicillin/sulbactam has been used as main prophylactic antibiotics after LT in Seoul National University Hospital (SNUH) according to the center protocol. The purpose of this study was to determine the incidence and risk factors for SSI after LT and to evaluate the appropriateness of prophylactic antibiotics. A total of 211 patients who underwent LT between July 2008 and June 2010 at SUNH were included. During study period, ampicillin/sulbactam was selected as prophylactic antibiotics in 140 patients (66.4%). A total of 43 patients (20.4%) developed infections and the incidence of SSI was noted in 28 patients (13.2%); 10.0% in ampicillin/sulbactam group and 19.4% in other antibiotics (p=0.049). The most common pathogen of SSI was MRSA (13 episodes, 49.4%). In multivariate analysis, choledochojejunostomy (OR: 7.0; 95% CI, 2.4-20.0) and lower serum albumin (OR: 3.7; 95% CI, 1.1-12.9) were found to be risk factors of SSIs. In conclusion, the incidence of SSIs after LT in this population was similar to those in other studies. Therefore, the prophylactic antibiotics protocol in LT at SNUH seems to be appropriate
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
American Society of Health-System Pharmacits / 1999 / ASHP therapeutic guideline on antimicrobial prophylaxis in surgery / Am J Health-Syst Pharm 56 : 1839 ~
Arnow PM / 1998 / Pathogenesis of early operative site infections after orthotopic liver transplantation / Transplantation 65 : 1500 ~ 1503
Asensio A / 2008 / Effect of antibiotic prophylaxis on the risk of surgical site infection in orthotopic liver transplant / Liver Transpl 14 (6) : 799 ~ 805
Blair JE / 2005 / Bacterial, mycobacterial, and protozoal infections after liver transplantation-Part I / Liver Transpl 11 (12) : 1452 ~ 1459
Chang FY / 1998 / Staphylococcus aureus nasal colonization and association with infections in liver transplant recipients / Transplantation 65 : 1169 ~ 1172
Arnow PM / 1998 / Pathogenesis of early operative site infections after orthotopic liver transplantation / Transplantation 65 : 1500 ~ 1503
Asensio A / 2008 / Effect of antibiotic prophylaxis on the risk of surgical site infection in orthotopic liver transplant / Liver Transpl 14 (6) : 799 ~ 805
Blair JE / 2005 / Bacterial, mycobacterial, and protozoal infections after liver transplantation-Part I / Liver Transpl 11 (12) : 1452 ~ 1459
Chang FY / 1998 / Staphylococcus aureus nasal colonization and association with infections in liver transplant recipients / Transplantation 65 : 1169 ~ 1172
이 논문의 저자 정보
최근 본 자료
댓글(0)
0