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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
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- 1 - 8 (8page)
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Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low-intensity direct current to cortical areas, thereby facilitating or inhibiting spontaneous neuronal activity. This study was designed to investigate changes in various sensory functions after tDCS. We conducted a single-center, single-blinded, randomized trial to determine the effect of a single session of tDCS with the current perception threshold (CPT) in 50 healthy volunteers. Nerve conduction studies were performed in relation to the median sensory and motor nerves on the dominant hand to discriminate peripheral nerve lesions. The subjects received anodal tDCS with 1 ㎃ for 15 minutes under two different conditions, with 25 subjects in each groups: the conditions were as follows tDCS on the primary motor cortex (M1) and sham tDCS on M1. We recorded the parameters of the CPT a with NeurometerⓇ at frequencies of 2000, 250, and 5 ㎐ in the dominant index finger to assess the tactile sense, fast pain and slow pain, respectively. In the test to measure CPT values of the M1 in the tDCS group, the values of the distal part of the distal interphalangeal joint of the second finger statistically increased in all of 2000 ㎐ (p=.000), 250 ㎐ (p=.002), and 5 ㎐ (p=.008). However, the values of the sham tDCS group decreased in all of 2000 ㎐ (p=.285), 250 ㎐ (p=.552), and 5 ㎐ (p=.062), and were not statistically significant. These results show that M1 anodal tDCS can modulate sensory perception and pain thresholds in healthy adult volunteers. The study suggests that tDCS may be a useful strategy for treating central neurogenic pain in rehabilitation medicine.
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참고문헌 (22)
참고문헌 신청
Antal A / 2007 / Towards unravelling task-related modulations of neuroplastic changes induced in the human motor cortex / Eur J Neurosci 26 (9) : 2687 ~ 2691
Boggio PS / 2008 / Modulatory effects of anodal transcranial direct current stimulation on perception and pain thresholds in healthy volunteers / Eur J Neurol 15 (10) : 1124
Cohen LG / 1991 / Attenuation in detection of somatosensory stimuli by transcranial magnetic stimulation / Electroencephalogr Clin Neurophysiol 81 (5) : 366 ~ 376
Drouot X / 2002 / The antalgic efficacy of chronic motor cortex stimulation is related to sensory changes in the painful zone / Brain 125 (Pt 7) : 1660 ~ 1664
Fecteau S / 2007 / Activation of prefrontal cortex by transcranial direct current stimulation reduces appetite for risk during ambiguous decision making / J Neurosci 27 (23)
Boggio PS / 2008 / Modulatory effects of anodal transcranial direct current stimulation on perception and pain thresholds in healthy volunteers / Eur J Neurol 15 (10) : 1124
Cohen LG / 1991 / Attenuation in detection of somatosensory stimuli by transcranial magnetic stimulation / Electroencephalogr Clin Neurophysiol 81 (5) : 366 ~ 376
Drouot X / 2002 / The antalgic efficacy of chronic motor cortex stimulation is related to sensory changes in the painful zone / Brain 125 (Pt 7) : 1660 ~ 1664
Fecteau S / 2007 / Activation of prefrontal cortex by transcranial direct current stimulation reduces appetite for risk during ambiguous decision making / J Neurosci 27 (23)
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