지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objectives: Although a great body of knowledge is available on the toxicity of bisphenol A (BPA), little is known about that of BPA alternatives, such as bisphenol analogues (BPs) or TritanTM copolyesters. This review provides a summary of the available information on the toxicity of BPs and three components of TritanTM, with a special focus on endocrine disruption.
Methods: We collected from the literature a battery of in vitro and in vivo assay data developed to assess endocrine disruption of four BPs (bisphenol AF, B, F, and S) and three major components of TritanTM ((di-methylterephthalate (DMT), 1,4-cyclohexanedimethanol (CHDM), and 2,2,4,4-tetramethyl-1,3-cyclobutanediol (TMCD)).
Results: Several alternative compounds were identified as possessing comparable or even greater endocrinedisrupting effects than BPA in in vitro and in vivo studies.
Conclusions: Potential endocrine disruption of BPA alternatives requires further studies on health consequences in experimental animals and in humans following longer term exposure.
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등록된 정보가 없습니다.
참고문헌 (52)
참고문헌 신청
Diamanti-Kandarakis E / 2009 / Endocrine- disrupting chemicals: an Endocrine society scientific statement / Endocrine Reviews 30:293~342
Liao C / 2012 / Bisphenol S in urine from the United States and seven Asian countries: occurrence and human exposures / Environ Sci Technol 46:6860~6866
Goodman JE / 2009 / Weight-of-evidence evaluation of reproductive and developmental effects of low doses of bisphenol A / Crit Rev Toxicol 39:1~75
Zhang X / 2011 / Bisphenol A disrupts steroidogenesis in human H295R cells / Toxicol Sci 121:320~327
Vandenberg LN / 2010 / Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A / Environ Health Perspect 118:1055~1070
Liao C / 2012 / Bisphenol S in urine from the United States and seven Asian countries: occurrence and human exposures / Environ Sci Technol 46:6860~6866
Goodman JE / 2009 / Weight-of-evidence evaluation of reproductive and developmental effects of low doses of bisphenol A / Crit Rev Toxicol 39:1~75
Zhang X / 2011 / Bisphenol A disrupts steroidogenesis in human H295R cells / Toxicol Sci 121:320~327
Vandenberg LN / 2010 / Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A / Environ Health Perspect 118:1055~1070
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