지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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This paper reports the development of a platform for tracking and analysis of animal locomotion. The platform is composed of a commercial webcam, a metal stand for the webcam, and a plastic bathtub as a cage. Using it, researchers can track and analyze an animal’s movement within the plastic bathtub’s dimensions of 100 cm×100 cm×55 cm in a cost-effective manner. After recording the locomotion of an animal with 1920×1080 resolution at a rate of 30 frames per second, finding the position of the animal in each frame and analyzing the ambulation pattern were executed with custom software. To evaluate the performance of the platform, movements of imprinting control region mice and transgenic mice were recorded and analyzed. The analysis successfully compared velocity, moving pattern, and total moving distance for the two mouse groups. In addition, the developed platform can be used not only in simple motion analysis but also in various experimental conditions, such as a water maze, by easy customization of the platform. Such a simple and cost-effective platform yields a powerful tool for animal ambulatory analysis.
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참고문헌 (13)
참고문헌 신청
A. Barker / 1992 / Role of amyloid beta-protein in Alzheimer's disease / Lancet 340 : 850 ~ 851
A. Samii / 2004 / Parkinson's disease / Lancet 363 : 1783 ~ 1793
E. Ericson / 1991 / Photocell measurements of rat motor activity. A contribution to sensitivity and variation in behavioral observations / J Pharmacol Methods 25 : 111 ~ 122
I. Tanida / 2002 / Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p t
J. N. Crawley / 1997 / A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice /
A. Samii / 2004 / Parkinson's disease / Lancet 363 : 1783 ~ 1793
E. Ericson / 1991 / Photocell measurements of rat motor activity. A contribution to sensitivity and variation in behavioral observations / J Pharmacol Methods 25 : 111 ~ 122
I. Tanida / 2002 / Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p t
J. N. Crawley / 1997 / A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice /
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