지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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A portable surface plasmon resonance(SPR) based immunosensor using thiolated protein G and protein G was developed for the detection of immunoglobulin G(IgG). The protein G has specific affinity with Fc fragment of IgG and was thiolated by 2-Iminothiolane for introduction of thiol groups. Anti-IgG, bovine serum albumin(BSA), and IgG have been sequently injected after surface modification of gold sensor chip with protein G and thiolated protein G. The output signal was increased with the injection of each protein and the actual signal was measured by subtracting signal of reference channel from signal of sample injected channel. The experimental results showed the higher detection capability of IgG using thiolated protein G compared with protein G. From these results, we can conclude that the current surface modification technique and the portable SPR sensor system can be applied to various immunosensors for diagnosis.
목차
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참고문헌 (16)
참고문헌 신청
A.M.Bond / 1994 / Past,present and future contributions of microelectrodes to analytical studies employing voltammetric detection.A review / Analyst 119 (11)
C. Bian / 2011 / A field effect transistor(FET)-based immunosensor for detection of HbA1c and Hb / Biomed. Microdevices 13 (2) : 345 ~ 352
K. Hegnerova / 2009 / Surface plasmon resonance biosensors for detection of Alzheimer disease biomarker / Sens. Actuators B Chem 139 (1) : 69 ~ 73
K. S. Lee / 2010 / Resolution enhancement in surface plasmon resonance sensor based on waveguide coupled mode by combining a bimetallic approach / Sensors 10 (12) : 11390 ~
K.A.Mark / 2003 / Quartz crystal microbalance:A useful tool for studying thin polymer films and complex biomolecular systems at the solution-surface Interface / Biomacromolec
C. Bian / 2011 / A field effect transistor(FET)-based immunosensor for detection of HbA1c and Hb / Biomed. Microdevices 13 (2) : 345 ~ 352
K. Hegnerova / 2009 / Surface plasmon resonance biosensors for detection of Alzheimer disease biomarker / Sens. Actuators B Chem 139 (1) : 69 ~ 73
K. S. Lee / 2010 / Resolution enhancement in surface plasmon resonance sensor based on waveguide coupled mode by combining a bimetallic approach / Sensors 10 (12) : 11390 ~
K.A.Mark / 2003 / Quartz crystal microbalance:A useful tool for studying thin polymer films and complex biomolecular systems at the solution-surface Interface / Biomacromolec
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