지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 67 - 72 (6page)
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초록· 키워드
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Background: Nowadays, although its clinical value remains controversial institutions utilize hair mineral analysis. Arguments about the reliability of hair mineral analysis persist, and there have been evaluations of commercial laboratories performing hair mineral analysis. Objective: The objective of this study was to assess the reliability of intra-laboratory and inter-laboratory data at three commercial laboratories conducting hair mineral analysis, compared to serum mineral analysis. Methods: Two divided hair samples taken from near the scalp were submitted for analysis at the same time, to all laboratories, from one healthy volunteer. Each laboratory sent a report consisting of quantitative results and their interpretation of health implications. Differences among intra-laboratory and inter- laboratory data were analyzed using SPSS version 12.0 (SPSS Inc., USA). Results: All the laboratories used identical methods for quantitative analysis, and they generated consistent numerical results according to Friedman analysis of variance. However, the normal reference ranges of each laboratory varied. As such, each laboratory interpreted the patient's health differently. On intra-laboratory data, Wilcoxon analysis suggested they generated relatively coherent data, but laboratory B could not in one element, so its reliability was doubtful. In comparison with the blood test, laboratory C generated identical results, but not laboratory A and B. Conclusion: Hair mineral analysis has its limitations, considering the reliability of inter and intra laboratory analysis comparing with blood analysis. As such, clinicians should be cautious when applying hair mineral analysis as an ancillary tool. Each laboratory included in this study requires continuous refinement from now on for inducing standardized normal reference levels.
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참고문헌 (14)
참고문헌 신청
Barrett S / 1985 / Commercial hair analysis. Science or scam? / JAMA 254 : 1041 ~ 1045
Bass DA / 2001 / Trace element analysis in hair: factors determining accuracy, precision, and reliability / Altern Med Rev 6 : 472 ~ 481
Drasch G / 2002 / Assessment of hair mineral analysis commercially offered in Germany / J Trace Elem Med Biol 16 : 27 ~ 31
Druyan ME / 1998 / Determination of reference ranges for elements in human scalp hair / Biol Trace Elem Res 62 : 183 ~ 197
Grabeklis AR / 2011 / Indicator ability of biosubstances in monitoring the moderate occupational exposure to toxic metals / J Trace Elem Med Biol 25 (Suppl 1) : S41 ~ S44
Bass DA / 2001 / Trace element analysis in hair: factors determining accuracy, precision, and reliability / Altern Med Rev 6 : 472 ~ 481
Drasch G / 2002 / Assessment of hair mineral analysis commercially offered in Germany / J Trace Elem Med Biol 16 : 27 ~ 31
Druyan ME / 1998 / Determination of reference ranges for elements in human scalp hair / Biol Trace Elem Res 62 : 183 ~ 197
Grabeklis AR / 2011 / Indicator ability of biosubstances in monitoring the moderate occupational exposure to toxic metals / J Trace Elem Med Biol 25 (Suppl 1) : S41 ~ S44
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