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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 10 - 14 (5page)
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Background: Vitamin D insufficiency could be associatedwith the prevalence of atopic dermatitis (AD). Objective: Toexamine vitamin D status and the relations between serum25-hydroxyvitamin D levels, SCORAD score, serum LL-37level, and body mass index (BMI) in Korean AD patients, andto explore whether these associations differ between adultsand children. Methods: Serum 25-hydroxyvitamin D levels,serum LL-37, and clinical features were analyzed in a total of72 Korean patients with AD (39 adults and 33 children) and140 healthy control subjects (70 adults and 70 children).
Results: Serum 25-hydroxyvitamin D levels were significantlyreduced in children with AD (15.06±4.64 ng/ml)compared with normal children in the control group(16.25±6.60 ng/ml) (p=0.036). Significant inverse correlationswere found between BMI and 25-hydroxyvitamin Dlevel (r=−0.315, p=0.007) and between the SCORADscore and serum LL-37 level (r=−0.3, p=0.011) in the totalAD patients. Conclusion: The results showed that serumvitamin D levels were lower in children with AD than inhealthy children; however, the same relation was notobserved between adults with AD and healthy adults. Serum25-hydroxyvitamin D concentration was not significantlycorrelated with AD severity or serum LL-37 levels in ourstudy population.
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참고문헌 (25)
참고문헌 신청
Benson AA / 2012 / The role of vitamin D in the immunopathogenesis of allergic skin diseases / Allergy 6 : 296 ~ 301
Brehm JM / 2009 / Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica / Am J Respir Crit Care Med 179 : 765 ~ 771
Brehm JM / 2010 / Childhood Asthma Management Program Research Group. Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study
Chinellato I / 2011 / Vitamin D serum levels and markers of asthma control in Italian children / J Pediatr 158 : 437 ~ 441
Chiu YE / 2013 / Serum 25-hydroxyvitamin D concentration does not correlate with atopic dermatitis severity / J Am Acad Dermatol 69 : 40 ~ 46
Brehm JM / 2009 / Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica / Am J Respir Crit Care Med 179 : 765 ~ 771
Brehm JM / 2010 / Childhood Asthma Management Program Research Group. Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study
Chinellato I / 2011 / Vitamin D serum levels and markers of asthma control in Italian children / J Pediatr 158 : 437 ~ 441
Chiu YE / 2013 / Serum 25-hydroxyvitamin D concentration does not correlate with atopic dermatitis severity / J Am Acad Dermatol 69 : 40 ~ 46
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