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자료유형
학술저널
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저널정보
대한피부과학회 Annals of Dermatology Annals of Dermatology 제26권 제4호
발행연도
2014.1
수록면
431 - 436 (6page)

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Background: Basal cell carcinoma (BCC) is the most commonform of skin cancer and possesses various clinicalfeatures including translucency, ulceration, pigmentation,telangiectasia, and rolled borders. Accordingly, many cutaneouslesions can mimic BCCs and differential diagnosis isdifficult. Objective: To clarify the differences in clinical characteristicsbetween BCCs and BCC-mimicking lesions(BMLs), and to determine which clinical characteristics arehelpful for an accurate clinical diagnosis of BCC. Methods:We performed clinicopathologic analysis of cutaneous lesionsthat received a clinical diagnosis of BCC. All lesionsincluded in this study showed more than one of the followingcharacteristics of BCCs: translucency, ulceration, fleckedpigmentation, black or blue hue, telangiectasia, and rolledborders. We compared six clinical characteristics betweenthe BCC group and the BML group. Results: Among 48lesions in the BML group, there were 15 premalignant ormalignant lesions and 33 benign lesions. Various dermatosesmimicking BCC that have not been reported in thedermatological literature were identified, including angiosarcoma,vulvar intraepithelial neoplasm, foreign body granuloma,intravascular papillary endothelial hyperplasia,sarcoidosis, and others. Compared to the BML group, theBCC group had a significantly higher frequency of translucency(76.3% vs. 52.1%, p<0.001), ulceration or erosion(44.2% vs. 27.1%, p=0.022), black or blue hue (40.0% vs. 22.9%, p=0.020), and rolled borders (49.5% vs. 14.6%, p<0.001). Cutaneous lesions with two or less clinical featuresof BCC were significantly more likely to be BMLs. Conclusion: The results of this study could be helpful for thedifferential diagnosis of BCCs and BCC-mimicking cutaneouslesions.

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