지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 177 - 183 (7page)
이용수
초록· 키워드
오류제보하기
Background: In cutaneous malignant melanoma (MM) withclinically uninvolved regional lymph nodes, sentinel lymphnode (SLN) status is the most powerful indicator of bothoverall survival (OS) and disease-free survival (DFS). However,no studies on the long-term survival and clinical follow-up ofKorean patients with acral lentiginous MM (ALM) undergoingSLN biopsy (SLNB) have been published. Objective:The purpose of this study was to investigate the clinicalprognosis and long-term survival of Korean patients withALM according to SLN status. Methods: Thirty-four ALMpatients undergoing SLNB were included in this study. Weevaluated clinical and histopathological follow-up data suchas the stage of disease, treatment, recurrence, and metastasis,and analyzed OS and DFS according to SLN status. Results:The median follow-up time was 60.5 months (range 3∼127months). Positive SLNs were noted in 14 patients (41.2%).
Patients with negative SLNs had better OS and DFS thanthose with positive SLNs (p＜0.05). Increased Breslowthickness was associated with short OS and DFS (p＜0.05),and female patients showed better DFS than male patients (p＜0.05). Conclusion: To our knowledge, this is the first studyon the long-term survival and clinical follow-up of patientsundergoing SLNB for ALM in Korea. Our findings show thatSLN status is an important prognostic factor for predicting OSand DFS.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Balch CM / 2001 / Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system / J Clin Oncol 19 : 3
Balch CM / 2009 / Final version of 2009 AJCC melanoma staging and classification / J Clin Oncol 27 : 6199 ~ 6206
Beitsch P / 1992 / Operative morbidity and risk factor assessment in melanoma patients undergoing inguinal lymph node dissection / Am J Surg 164 : 462 ~ 465
Breslow A / 1975 / Tumor thickness, level of invasion and node dissection in stage I cutaneous melanoma / Ann Surg 182 : 572 ~ 575
Crowley NJ / 1990 / The role of elective lymph node dissection in the management of patients with thick cutaneous melanoma / Cancer 66 : 2522 ~ 2527
Balch CM / 2009 / Final version of 2009 AJCC melanoma staging and classification / J Clin Oncol 27 : 6199 ~ 6206
Beitsch P / 1992 / Operative morbidity and risk factor assessment in melanoma patients undergoing inguinal lymph node dissection / Am J Surg 164 : 462 ~ 465
Breslow A / 1975 / Tumor thickness, level of invasion and node dissection in stage I cutaneous melanoma / Ann Surg 182 : 572 ~ 575
Crowley NJ / 1990 / The role of elective lymph node dissection in the management of patients with thick cutaneous melanoma / Cancer 66 : 2522 ~ 2527
이 논문의 저자 정보
최근 본 자료
댓글(0)
0