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자료유형
학술저널
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저널정보
대한피부과학회 Annals of Dermatology Annals of Dermatology 제28권 제2호
발행연도
2016.1
수록면
199 - 204 (6page)

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Background: Thyroid autoimmunity has been increasingly reported to be associated with chronic urticaria (CU), and the possible clinical benefit of thyroid hormone or anti-thyroid drugs in some CU patients with autoimmune thyroid disease has been studied. However, the effect of thyroid hormone or anti-thyroid drugs on clinical symptoms of CU remains unclear. Objective: We investigated the clinical response of urticaria to the treatment of thyroid dysfunction. Methods: Medical records of patients with CU evaluated for thyroid autoimmunity and thyroid function were collected and reviewed. Results: Of 184 patients with CU, 43 patients (23.4%) had thyroid autoantibodies and 26 patients (14.1%) had thyroid dysfunction. While none of the five patients with Graves’ disease showed any improvement of urticaria after treatment with anti-thyroid drugs, two of the 10 patients with Hashimoto’s thyroiditis showed improved urticaria after being treated with levothyroxine. Conclusion: Although levothyroxine treatment was effective in a minority of patients with CU, there may be a causal relationship between CU and thyroid autoimmunity.

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