지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 575 - 580 (6page)
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초록· 키워드
오류제보하기
Background: Cutaneous leishmaniasis is a tropical infection of public health importance. Numerous treatment approaches are in practice with variable degree of success however its management has no universal consensus or practice guidelines to follow. Objective: Analyze the management of cutaneous leishmaniasis retrospectively at a central hospital of Jazan Province, Kingdom of Saudi Arabia to identify the current treatment pattern and compare the outcomes. Methods: This cross-sectional study was conducted based on the hospital records of patients who attended the dermatology clinic for cutaneous leishmaniasis during the year 2012 to 2015. Results: Forty three patients were included in the study. There was a male preponderance (65.1%) among the patients and 60.5% of them were of pediatric age group. Monotherapy was the initial choice for 58.1% of the patients. Intralesional sodium stibogluconate (SS-IL) was the most preferred treatment for initial therapy, as monotherapy and as part of combination therapy. A complete response was achieved in 22 patients (51.2%) with initial therapy. Among the different treatment groups, SS-IL+itraconazole showed significantly higher complete response rate compared to other treatments offered as initial therapy (p＜0.01). Initial SS-IL monotherapy provided complete response in 41.2% patients receiving it, while itraconazole monotherapy provided complete response in 75% and 90.9% of the patients receiving initial itraconazole+SS-IL combination therapy with achieved complete response. Conclusion: The findings and observations suggest that initial combination therapy with SS-IL+itraconazole significantly improved the complete response rates and thus reduced the need for additional or prolonged therapies.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Murray HW / 2005 / Advances in leishmaniasis / Lancet 366:1561~1577
Salam N / 2014 / Leishmaniasis in the middle east: incidence and epidemiology / PLoS Negl Trop Dis 8:e3208
Reithinger R / 2007 / Cutaneous leishmaniasis / Lancet Infect Dis 7:581~596
Lahiru Sandaruwan Galgamuwa / 2017 / Clinico-Epidemiological Patterns of Cutaneous Leishmaniasis Patients Attending the Anuradhapura Teaching Hospital, Sri Lanka / The Korean Journal of Parasitology 55(1):1~7
Hepburn NC / 2003 / Cutaneous leishmaniasis: current and future management / Expert Rev Anti Infect Ther 1:563~570
Salam N / 2014 / Leishmaniasis in the middle east: incidence and epidemiology / PLoS Negl Trop Dis 8:e3208
Reithinger R / 2007 / Cutaneous leishmaniasis / Lancet Infect Dis 7:581~596
Lahiru Sandaruwan Galgamuwa / 2017 / Clinico-Epidemiological Patterns of Cutaneous Leishmaniasis Patients Attending the Anuradhapura Teaching Hospital, Sri Lanka / The Korean Journal of Parasitology 55(1):1~7
Hepburn NC / 2003 / Cutaneous leishmaniasis: current and future management / Expert Rev Anti Infect Ther 1:563~570
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