지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 36 - 40 (5page)
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초록· 키워드
오류제보하기
Background: Prevalence of subungual melanoma (SUM) in Asian population is relatively high and early clinical detection improves both quality of life and survival. Objective: We sought to establish screening strategy for SUM in situ. Methods: We retrospectively reviewed medical records of 8 patients pathologically diagnosed as SUM in situ between January 2015 and September 2016. Results: All patients in our study were adults and had solitary lesion. In all cases, longitudinal melanonychia as well as background pigmentation in entire nail plate was observed. Seven (87.5%) cases had periungual pigmentation. Clinical features of SUM in situ can be summarized according to new criteria categorized under initial letters of alphabet, namely nail ABCD of SUM in situ; “A” stands for adult age (age ＞18 years); “B” for brown bands in brown background; “C” for color in periungual skin; “D” for one digit. Our strategy was to suspect SUM in situ if solitary longitudinal melanonychia in adult was satisfying either “B” or “C” in ABCD. All cases were suspected as SUM in situ under nail ABCD rule, and histological examination confirmed diagnosis. Sensitivity and specificity of nail ABCD was 100% and 96.6%, respectively, regarding our previously published 18 SUM in situ and unpublished 28 nail matrix nevi cases as well as 8 SUM in situ presented here. Conclusion: ABCD rule is simple and sensitive clinical strategy for early detection of SUM in situ.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
High WA / 2004 / Presentation, histopathologic findings, and clinical outcomes in 7 cases of melanoma in situ of the nail unit / Arch Dermatol 140:1102~1106
Duarte AF / 2015 / Nail melanoma in situ: clinical, dermoscopic, pathologic clues, and steps for minimally invasive treatment / Dermatol Surg 41:59~68
Saida T / 1989 / Clinical and histopathologic characteristics of early lesions of subungual malignant melanoma / Cancer 63:556~560
Park SW / 2016 / Scattered atypical melanocytes with hyperchromatic nuclei in the nail matrix: diagnostic clue for early subungual melanoma in situ / J Cutan Pathol 43:41~52
Ishihara Y / 1993 / Detection of early lesions of "ungual" malignant melanoma / Int J Dermatol 32:44~47
Duarte AF / 2015 / Nail melanoma in situ: clinical, dermoscopic, pathologic clues, and steps for minimally invasive treatment / Dermatol Surg 41:59~68
Saida T / 1989 / Clinical and histopathologic characteristics of early lesions of subungual malignant melanoma / Cancer 63:556~560
Park SW / 2016 / Scattered atypical melanocytes with hyperchromatic nuclei in the nail matrix: diagnostic clue for early subungual melanoma in situ / J Cutan Pathol 43:41~52
Ishihara Y / 1993 / Detection of early lesions of "ungual" malignant melanoma / Int J Dermatol 32:44~47
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