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자료유형
학술저널
저자정보
저널정보
대한피부과학회 Annals of Dermatology Annals of Dermatology 제26권 제6호
발행연도
2014.1
수록면
688 - 692 (5page)

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Background: Formaldehyde (FA) and other volatile organiccompounds (VOCs) are considered among the main causesof atopic aggravation. Their main sources include wallpapers,paints, adhesives, and flooring materials. Objective:To assess the effects of environmentally friendly wallpaperand flooring material on indoor air quality and atopicdermatitis severity. Methods: Thirty patients with atopicdermatitis were enrolled in this study. To improve air quality,the wallpaper and flooring in the homes of the subjects werereplaced with plant- or silica-based materials. The indoor airconcentration of FA and the total VOCs (TVOCs) weremeasured before remodeling and 2, 6, and 10 weeksthereafter. Pruritus and the severity of atopic eczema wereevaluated by using a questionnaire and the eczema area andseverity index (EASI) score before and at 4, 8, and 12 weeksafter remodeling. The subjects were instructed to continuetheir therapy for atopic dermatitis. Results: The houses of 24subjects were remodeled; all subjects completed the study. The concentration of FA in ambient air significantlydecreased within 2 weeks after remodeling. The TVOC levelshowed a decrease at week 2 but increased again at weeks6 and 10. The reduction of pruritus and EASI score wasstatistically significant in patients whose baseline EASI scorewas >3. Conclusion: Replacing the wallpaper and flooringof houses with environmentally friendly material reduced FAin ambient air and improved pruritus and the severity ofatopic eczema. The improvement of pruritus and eczemawas statistically significant in patients whose baseline EASIscore was >3.

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