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Background: Androgenetic alopecia (AGA) is a common hair loss disease with genetic predisposition among men and women, and it may commence at any age after puberty. It may significantly affect a variety of psychological and social aspects of one’s life and the individual’s overall quality of life (QoL). Objective: This study aimed to investigate the QoL of AGA patients and discover the factors that can influence the QoL of AGA patients, including previous experience in non-medical hair care, reasons for hospital visits, age,duration, and the severity of AGA. Methods: A total of 998male patients with AGA were interviewed, using the Hair Specific Skindex-29 to evaluate the QoL of AGA patients. Results: The results of the Hair Specific Skindex-29 on patients with AGA were as follows: symptom scale:26.3±19.5, function scale: 24.0±20.1, emotion scale:32.1±21.8, and global score: 27.3±19.1. According to this assessment, QoL was more damaged if the patient had severe alopecia, a longer duration of AGA, younger age, had received previous non-medical hair care, and visited the hospital for AGA treatment. Conclusion: This study showed that AGA could harmfully affect the patients’ QoL. These findings indicate that dermatologists should address these QoL issues when treating patients with alopecia.

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