지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 139 - 144 (6page)
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초록· 키워드
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Background: To manage intractable cancer pain, an alternative to systemic analgesics is neuraxial analgesia. In long-term treatment, intrathecal administration could provide a more satisfactory pain relief with lower doses of analgesics and fewer side-effects than that of epidural administration. However, implantable drug delivery systems using intrathecal pumps in Korea are very expensive. Considering cost-effectiveness, we performed epidural analgesia as an alternative to intrathecal analgesia.
Methods: We retrospectively investigated the efficacy, side effects, and complications of epidural morphine and local anesthetic administration through epidural catheters connected to a subcutaneous injection port in 29 Korean terminal cancer patients. Patient demographic data, the duration of epidural administration, preoperative numerical pain rating scales (NRS), side effects and complications related to the epidural catheterization and the drugs, and the numerical pain rating scales on the 1st, 3rd, 7th and 30th postoperative days were determined from the medical records.
Results: The average score for the numerical pain rating scales for the 29 patients decreased from 7 ± 1.0 at baseline to 3.6 ± 1.4 on postoperative day 1 (P ＜ 0.001). A similar decrease in pain intensity was maintained for 30 days (P ＜ 0.001). Nausea and vomiting were the most frequently reported side effects of the epidural analgesia and two patients (6.9%) experienced paresthesia.
Conclusions: Epidural morphine and local anesthetic infusion with a subcutaneous pump seems to have an acceptable risk-benefit ratio and allows a high degree of autonomy to patients with cancer pain.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Aldrete JA / 2004 / Intrathecal opioid infusions / Anesthesiology 101 : 256 ~
Bedder MD / 1991 / Cost analysis of two implantable narcotic delivery systems / J Pain Symptom Manage 6 : 368 ~ 373
Carde P / 1989 / Classical external indwelling central venous catheter versus totally implanted venous access systems for chemotherapy administration : a randomized trial in
Crul BJ / 1991 / Technical complications during long-term subarachnoid or epidural administration of morphine in terminally ill cancer patients : a review of 140cases / Reg A
De Cicco M / 1995 / Time-dependent efficacy of bacterial filters and infection risk in long-term epidural catheterization / Anesthesiology 82 : 765 ~ 771
Bedder MD / 1991 / Cost analysis of two implantable narcotic delivery systems / J Pain Symptom Manage 6 : 368 ~ 373
Carde P / 1989 / Classical external indwelling central venous catheter versus totally implanted venous access systems for chemotherapy administration : a randomized trial in
Crul BJ / 1991 / Technical complications during long-term subarachnoid or epidural administration of morphine in terminally ill cancer patients : a review of 140cases / Reg A
De Cicco M / 1995 / Time-dependent efficacy of bacterial filters and infection risk in long-term epidural catheterization / Anesthesiology 82 : 765 ~ 771
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